Protein Alignment AdoR and chrm1

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_004913717.1
• Gene: chrm1 / 100490434
• XenbaseID: XB-GENE-22061118
• Length: 521
• Species: Xenopus tropicalis
• Alignment Length: 465
• Identity: 107/465 - (23%)
• Similarity: 167/465 - (35%)
• Gaps: 166/465 - (35%)

  Fly    44 YTVFEV--------LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGI----P 96
            :.|:||        ::::|::||||||::.|:....|:...||:::|||.||:::|||.:    .
 Frog    42 HAVWEVVLIVITTGILSLVTVIGNVLVLLAFKVNSDLKTVNNYFLLSLACADIIIGALSMNLYTT 106

  Fly    97 FAILASMGLPRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIIS 161
            :.::....|  ...:|...::|..|....|:..|:.:|.|||::|..|:.|......|.|..:|.
 Frog   107 YIVMGRWAL--GPVSCDLWLALDYVASNASVMNLLIISFDRYFSITRPLTYRAKRTPRRAAIMIG 169

  Fly   162 MCWVAGTIVGFLPLFGWHADVNHNQECLFVEVMDYNYLVF-----LYFATIIT----PALLMLAF 217
            |.|....::....:..|...|....    ||..|. |:.|     :.|.|.|.    |..:|:..
 Frog   170 MAWFISFVLWAPAIIFWQYIVGERT----VEATDC-YIQFFSQPIITFGTAIAAFYLPVTIMIIL 229

  Fly   218 YTHIYRVIIKQVRQI-------------------------------------------------- 232
            |..:||....:.:::
 Frog   230 YWRVYRETENRSKELAGLQGSGTDHTSHPLALGSVRSGSSSGAGESERLSRGQRTVPRAKQGCCF 294

  Fly   233 ---VTMNP----------------------ASDLSRRSSA------------AVVQ-------VT 253
               :|.||                      |..||..|.|            ||::       |.
 Frog   295 PRQLTSNPSLRSYPEHRSNGSCNTMEDAASADSLSSSSEAEDRPYEMKNICSAVIRLPMVSSVVG 359

  Fly   254 TP----------GRG-------GHTGTMLRVLGAA---------------------RK-----RD 275
            ||          |||       |....:.|....|                     ||     ::
 Frog   360 TPKGSRGSSDTLGRGDIEAETNGGKSEVTRKTSRAQVTALPSTIIRAKSEKNHHGKRKSNSLIKE 424

  Fly   276 VKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCIILSHLNSAVNPVLYAYHLKD 340
            .||.:.||.|:|.|::.|.|...:..:..||||| |..||......|.::||.|||:.||...:.
 Frog   425 KKAAKTLSAILLAFILTWTPYNIMVLVSTFCPDC-VPKKLWELGYWLCYVNSTVNPMCYALCNRS 488

  Fly   341 FRAALKNLLL 350
            ||...|.|||
 Frog   489 FRRTFKMLLL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	50/180 (28%)
		7tm_1	58..334	CDD:278431	94/425 (22%)
chrm1	XP_004913717.1	7tmA_mAChR_M1	48..493	CDD:341356	100/452 (22%)
		TM helix 1	49..75	CDD:341356	8/25 (32%)
		TM helix 2	82..108	CDD:341356	10/25 (40%)
		TM helix 3	120..150	CDD:341356	9/29 (31%)
		TM helix 4	162..185	CDD:341356	5/22 (23%)
		TM helix 5	207..236	CDD:341356	7/28 (25%)
		TM helix 6	422..452	CDD:341356	9/29 (31%)
		TM helix 7	461..486	CDD:341356	10/24 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910