DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and LOC100490372

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_002937327.2	Gene:	LOC100490372 / 100490372	-ID:	-	Length:	405	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	101/342 - (29%)
Similarity:	163/342 - (47%)	Gaps:	48/342 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LVAIVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAIL---ASMGLPRNLHA 111
            ::.:::.:||.:|.|....|::||..|..:|:|||||||||..|.:||:|:   ..|.| .....
Frog    64 VIDLITFLGNAVVFICPVVEKRLRTVTYMFIMSLAMADLLVACLVMPFSIIYEVTGMWL-FGKQF 127

  Fly   112 CLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLF 176
            |...:|..|:.||.||..|..:|:|||.:::.|..||:.:..|..|.:....||..:::.|||:.
Frog   128 CKVWISFDVMFCTASIVTLCFISLDRYCSVVTPYHYSKRMSRRRCIIMTVTIWVYSSLISFLPVM 192

  Fly   177 -GWH----ADVNHNQECLFVEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMN 236
             ||:    .|.::.::|:|  |.::.:.:.........|.::|.:.|..|||.
Frog   193 QGWNEIPGVDTDNGKQCIF--VTNWTFAIVASSLAFYIPFIIMCSMYFFIYRA------------ 243

  Fly   237 PASDLSRRSSAAVVQVTT-----PGRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPL 296
                 ||..:..:|..|.     |.........|         :.|||:.:.||:..|::||:|.
Frog   244 -----SRLKATRIVSQTLDLHYHPNSKRQNNLQL---------ENKATRTMGIIISVFVMCWLPY 294

  Fly   297 YTIN-CIKAFCPDCYVHPKLTLFCII--LSHLNSAVNPVLYAYHLKDFRAALKNLLL---KMMGV 355
            :.:| .|.|...|......:..|..|  |.:.||.:||:|||:..:||:.|||.||:   ....|
Frog   295 FVLNVLIAAKGTDSTSRVLVNAFKFITWLGYCNSTINPMLYAFLNRDFQRALKKLLICRRWRSQV 359

  Fly   356 DIDQQAEAIHRFSVASQ 372
            ||.....:|..||..:|
Frog   360 DIGDDMVSIVTFSKTAQ 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	55/175 (31%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	84/291 (29%)
LOC100490372	XP_002937327.2	7tmA_amine_R-like	58..346	CDD:320098	89/310 (29%)
		TM helix 1	58..83	CDD:320098	4/18 (22%)
		TM helix 2	90..117	CDD:320098	15/26 (58%)
		TM helix 3	128..158	CDD:320098	12/29 (41%)
		TM helix 4	170..190	CDD:320098	5/19 (26%)
		TM helix 5	214..270	CDD:320098	11/72 (15%)
		TM helix 6	271..301	CDD:320098	11/38 (29%)
		TM helix 7	311..339	CDD:320098	10/27 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910