DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdoR and LOC100489056

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	NP_001265680.1	Gene:	LOC100489056 / 100489056	-ID:	-	Length:	382	Species:	Xenopus tropicalis

Alignment Length:	429	Identity:	94/429 - (21%)
Similarity:	164/429 - (38%)	Gaps:	113/429 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 FEGPLLPLHAATTSKDAKDSDSPSSELNIPYTVFEVLVAI------VSIIGNVLVIIVFRRERKL 72
            |.|||..:.|..                     |.:|.|:      :||..|.:||:|..:.::|
Frog    20 FTGPLKTIEAWN---------------------FHLLAALMFVVTSLSIAENFIVILVTAKFKQL 63

  Fly    73 RRRTNYYIVSLAMADLLVGALGIPFAILAS------MGLPRNLHACLFTVSLLVVLCTISIFCLV 131
            |:..||.||:|::||.||..:|...:|..:      :|    ..||:.....:.....::::.|.
Frog    64 RQPLNYIIVNLSVADFLVSVIGGTISIATNSRGYFYLG----SWACVLEGFAVTFFGIVALWSLS 124

  Fly   132 AVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPLFGW--HADVNHNQEC----LF 190
            .::.:||..|..|:...|.....:|:.|| ..||...:....|..||  :........|    ..
Frog   125 VLAFERYIVICRPLGNLRLQGKHSALAII-FVWVFSFVWTIPPTMGWSSYTTSKIGTTCEPNWYS 188

  Fly   191 VEVMDYNYLVFLYFATIITPALLMLAFYTHIYRVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTP 255
            .|:.|:.|::.......:.|.|::...|..:.|.:.|          .||             |.
Frog   189 GEMRDHTYIITFLTTCFVFPLLVIFMSYGKLMRKLRK----------VSD-------------TQ 230

  Fly   256 GRGGHTGTMLRVLGAARKRDVKATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCI 320
            ||          ||:.||.:.:.|:.:.|::|.|:|||.|....:.:....|...:.|:|.....
Frog   231 GR----------LGSTRKPEKEVTRMVVIMILAFLICWTPYAAFSILITAHPTIDLDPRLAAIPA 285

  Fly   321 ILSHLNSAVNPVLYAYHLKDFRAALKNLLLKMMGVDIDQQAEAIHRFSVASQHRLQSMDSNMRST 385
            ..:...|..||::|.|..|.||    ..|.:|..:: |.:|:                :||:..|
Frog   286 FFAKTASMYNPIIYVYMNKQFR----RCLYQMFNIN-DPEAK----------------ESNLNPT 329

  Fly   386 QPR------------LYVGEY---SPIWLRQQQEALKNS 409
            ..|            |.:..:   |.:..|:::::..||
Frog   330 SERGVLTRNNNGGEMLAIATHITSSAVTNREEEKSSSNS 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	44/185 (24%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	66/287 (23%)
LOC100489056	NP_001265680.1	7tmA_VA_opsin	20..310	CDD:320210	81/352 (23%)
		TM helix 1	34..60	CDD:320210	8/25 (32%)
		TM helix 2	67..94	CDD:320210	11/26 (42%)
		TM helix 3	105..135	CDD:320210	4/29 (14%)
		TM helix 4	148..166	CDD:320210	5/18 (28%)
		TM helix 5	193..223	CDD:320210	6/29 (21%)
		TM helix 6	238..268	CDD:320210	9/29 (31%)
		TM helix 7	278..303	CDD:320210	7/24 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910