DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment AdoR and LOC100488258

DIOPT Version :9

Sequence 1:	NP_651772.1	Gene:	AdoR / 43583	FlyBaseID:	FBgn0039747	Length:	774	Species:	Drosophila melanogaster
Sequence 2:	XP_012818683.1	Gene:	LOC100488258 / 100488258	-ID:	-	Length:	333	Species:	Xenopus tropicalis

Alignment Length:	333	Identity:	86/333 - (25%)
Similarity:	148/333 - (44%)	Gaps:	79/333 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 IVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLLVGALGIPFAILASM-------GLPRNLH 110
            |::.:||:||||.....|:|...||:.|:|||.||.|:|.:.:|::::.|:       .|...:|
Frog    34 ILTTVGNLLVIISISHFRQLHYPTNFLILSLATADFLIGLVVMPYSMVRSLTSCWYFGDLFCKVH 98

  Fly   111 ACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVRTRTAIFIISMCWVAGTIVGFLPL 175
            :||.     :.|||.||:.|..:|||||:|:.:|:.|.:|:.|......:...|....:..|..:
Frog    99 SCLD-----MTLCTGSIYHLFFISVDRYYAVCHPLHYYKNLTTNVIELFLLTTWSVSCVFSFGLV 158

  Fly   176 FGWHADVNHNQECLFVEVMDYNYLVFLY------------FATI------ITPALLMLAFYTHIY 222
            |.     |.:.|.:      .:|:...|            :.||      ..|..||:..|.||:
Frog   159 FS-----NVHTEGI------QDYITSYYCIGSCSLTLNKLWGTISSLICFFIPGALMIGIYMHIF 212

  Fly   223 RVIIKQVRQIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARKRDVKATQNLSIIVL 287
            .|...|.:.:...:.......:|..:|                       :.:.||.:.|||::.
Frog   213 SVARNQAKLVHNHHSFQPDKSKSKISV-----------------------RAERKAAKTLSIVMG 254

  Fly   288 FFMICWIPLYTINCIKAFCPDCYVH---PKLTLFCII--LSHLNSAVNPVLYA----YHLKDFRA 343
            .|:.||:|.:.:..|     |.|::   |: .|:.:.  |.:.|||:||::||    :..|.|..
Frog   255 VFLFCWLPFFILTVI-----DPYINFSVPE-DLYNVFLWLGYFNSALNPIIYALFYPWFQKAFAC 313

  Fly   344 ALKNLLLK 351
            .:...:||
Frog   314 IISGNILK 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	54/191 (28%)
AdoR	NP_651772.1	7tm_1	58..334	CDD:278431	79/305 (26%)
LOC100488258	XP_012818683.1	7tmA_TAAR2_3_4	23..311	CDD:320437	83/321 (26%)
		TM helix 1	24..50	CDD:320437	7/15 (47%)
		TM helix 2	57..83	CDD:320437	11/25 (44%)
		TM helix 3	95..125	CDD:320437	15/34 (44%)
		TM helix 4	137..160	CDD:320437	2/22 (9%)
		TM helix 5	185..214	CDD:320437	8/28 (29%)
		TM helix 6	240..270	CDD:320437	10/34 (29%)
		TM helix 7	279..304	CDD:320437	9/25 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910