Protein Alignment AdoR and chrm2

DIOPT Version :9

• Sequence 1: NP_651772.1
• Gene: AdoR / 43583
• FlyBaseID: FBgn0039747
• Length: 774
• Species: Drosophila melanogaster
• Sequence 2: XP_002942846.2
• Gene: chrm2 / 100485603
• XenbaseID: XB-GENE-6034896
• Length: 470
• Species: Xenopus tropicalis
• Alignment Length: 466
• Identity: 100/466 - (21%)
• Similarity: 160/466 - (34%)
• Gaps: 163/466 - (34%)

  Fly    33 SDSPSSELNIPY----TVFEVLVA----IVSIIGNVLVIIVFRRERKLRRRTNYYIVSLAMADLL 89
            |.:..:.:..||    .||.|:||    :|:||||:||::..:..|.|:...||::.|||.|||:
 Frog    10 SSTNETMMGSPYKTVEVVFIVIVAGSLSLVTIIGNILVMVSIKVNRHLQTVNNYFLFSLACADLI 74

  Fly    90 VGALGIP-FAILASMGL-PRNLHACLFTVSLLVVLCTISIFCLVAVSVDRYWAILYPMAYSRNVR 152
            :|...:. :.:...:|. |.....|...::|..|:...|:..|:.:|.|||:.:..|:.|.....
 Frog    75 IGVFSMNLYTLYTVIGYWPIGPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPVRRT 139

  Fly   153 TRTAIFIISMCWVAGTIVGFLPLFGWHADVNHNQ----ECLFVEVMDYNYLVF-----LYFATII 208
            |:.|..:|:..||...|:....:..|...|....    ||         |:.|     :.|.|.|
 Frog   140 TKMAGMMIAAAWVLSFILWAPAILFWQFIVGGRTVPEGEC---------YIQFFSNAAVTFGTAI 195

  Fly   209 T----PALLMLAFYTHIYRVIIKQVR--------------------------------------- 230
            .    |.::|...|..|.|....:::
 Frog   196 AAFYLPVIIMTVLYWQISRASKSRIKKGKKEAAPNQDPISPSNVQGKIVKPNNNNVAANEDGLDH 260

  Fly   231 ----------------------------------------------------------------- 230
                                                                             
 Frog   261 GKIQNGKVTSNSGIENCVQAEGEEKEISNDSTSVSVVNTKDEGAAKDVPQASGSQANPKTENSKL 325

  Fly   231 ---QIVTMNPASDLSRRSSAAVVQVTTPGRGGHTGTMLRVLGAARK----------------RDV 276
               :|||.:|..|.|..:...|..|  ||..|..|...:.: .|||                |:.
 Frog   326 TCIRIVTKSPKGDCSNATGTTVEIV--PGANGRNGEDKQNI-VARKIVKMTKQPPKKKLPPSREK 387

  Fly   277 KATQNLSIIVLFFMICWIPLYTINCIKAFCPDCYVHPKLTLFCI--ILSHLNSAVNPVLYAYHLK 339
            |.|:.:..|:|.|:|.|.|...:..|..||..|..:   |::.|  .|.::||.:||..||....
 Frog   388 KVTRTILAILLAFIITWTPYNVMVLINTFCAVCVPN---TVWTIGYWLCYINSTINPACYALCNT 449

  Fly   340 DFRAALKNLLL 350
            .|:...|:||:
 Frog   450 TFKKTFKHLLM 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AdoR	NP_651772.1	7tm_4	52..>220	CDD:304433	50/186 (27%)
		7tm_1	58..334	CDD:278431	83/415 (20%)
chrm2	XP_002942846.2	7tmA_mAChR_M2	27..455	CDD:320424	94/442 (21%)
		TM helix 1	29..53	CDD:320424	10/23 (43%)
		TM helix 2	62..84	CDD:320424	9/21 (43%)
		TM helix 3	100..122	CDD:320424	4/21 (19%)
		TM helix 4	145..161	CDD:320424	4/15 (27%)
		TM helix 5	187..210	CDD:320424	5/22 (23%)
		TM helix 6	390..412	CDD:320424	7/21 (33%)
		TM helix 7	423..448	CDD:320424	9/27 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910