DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment AdoR and cxcr4

DIOPT Version :9

Sequence 1:NP_651772.1 Gene:AdoR / 43583 FlyBaseID:FBgn0039747 Length:774 Species:Drosophila melanogaster
Sequence 2:NP_001090831.1 Gene:cxcr4 / 100038176 XenbaseID:XB-GENE-489917 Length:358 Species:Xenopus tropicalis


Alignment Length: Identity:/ - (0%)
Similarity:/ - (0%) Gaps:/ - (0%)


- Green bases have known domain annotations that are detailed below.


Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
AdoRNP_651772.1 7tm_4 52..>220 CDD:304433
7tm_1 58..334 CDD:278431
cxcr4NP_001090831.1 Important for chemokine binding and signaling. /evidence=ECO:0000250 1..25
CXCR4_N 10..42 CDD:371902
7tmA_CXCR4 43..320 CDD:341334
TM helix 1 43..70 CDD:341334
TM helix 2 77..102 CDD:341334
Chemokine binding. /evidence=ECO:0000250 98..101
TM helix 3 113..143 CDD:341334
Chemokine binding. /evidence=ECO:0000250 117..121
Involved in dimerization, when bound to chemokine. /evidence=ECO:0000250 139..151
TM helix 4 155..177 CDD:341334
Chemokine binding, important for signaling. /evidence=ECO:0000250 190..194
TM helix 5 203..232 CDD:341334
TM helix 6 239..269 CDD:341334
TM helix 7 288..313 CDD:341334
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 338..358
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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