DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpi and TIM

DIOPT Version :9

Sequence 1:	NP_788764.1	Gene:	Tpi / 43582	FlyBaseID:	FBgn0086355	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_001323967.1	Gene:	TIM / 816652	AraportID:	AT2G21170	Length:	315	Species:	Arabidopsis thaliana

Alignment Length:	292	Identity:	149/292 - (51%)
Similarity:	194/292 - (66%)	Gaps:	15/292 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 VFPKLFKCQWKTYEGQKKFY-ANFSTDCTDSNSNNM-----------SRKFCVGGNWKMNGDQKS 120
            :.|||......::  |..|: .|.||....|:|::.           |.||.||||||.||.:.|
plant    18 ISPKLDAAAVSSH--QSFFHRVNSSTRLVSSSSSSHRSPRGVVAMAGSGKFFVGGNWKCNGTKDS 80

  Fly   121 IAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLPCELGLAGQNAYKVAKGAFTGEISPAMLKD 185
            ||::...|:||.|:.:.:||:..|.:|:...::.|...:.::|||::....||||||||...|||
plant    81 IAKLISDLNSATLEADVDVVVSPPFVYIDQVKSSLTDRIDISGQNSWVGKGGAFTGEISVEQLKD 145

  Fly   186 IGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEEREAGKTNEVVARQMCAY 250
            :|..||||||||||.:.||.|..|.:||.:||:|||.|||||||.|||||||||.:|...|:.|:
plant   146 LGCKWVILGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAF 210

  Fly   251 AQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISKEVSASLRIQYGGSVTAA 315
            |..:..|.|:|||||||||||||:.|:|.||||||..:|.||..|:|:||::..||.|||||...
plant   211 ADAVPSWDNIVVAYEPVWAIGTGKVASPQQAQEVHVAVRGWLKKNVSEEVASKTRIIYGGSVNGG 275

  Fly   316 NAKELAKKPDIDGFLVGGASLK-PEFVDIINA 346
            |:.||||:.||||||||||||| |||..|:|:
plant   276 NSAELAKEEDIDGFLVGGASLKGPEFATIVNS 307

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpi	NP_788764.1	PTZ00333	102..346	CDD:240365	138/255 (54%)
TIM	NP_001323967.1	PLN02429	1..315	CDD:166070	149/292 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	271	1.000	Domainoid score	I438
eggNOG	1	0.900	-	-		E1_COG0149
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	278	1.000	Inparanoid score	I885
OMA	1	1.010	-	-		QHG62471
OrthoDB	1	1.010	-	-		D1272577at2759
OrthoFinder	1	1.000	-	-		FOG0002444
OrthoInspector	1	1.000	-	-		otm3020
orthoMCL	1	0.900	-	-		OOG6_100657
Panther	1	1.100	-	-	O	PTHR21139
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1627
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840