DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpi and tpi1b

DIOPT Version :9

Sequence 1:	NP_788764.1	Gene:	Tpi / 43582	FlyBaseID:	FBgn0086355	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_705954.2	Gene:	tpi1b / 560753	ZFINID:	ZDB-GENE-020416-4	Length:	248	Species:	Danio rerio

Alignment Length:	244	Identity:	166/244 - (68%)
Similarity:	191/244 - (78%)	Gaps:	0/244 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 RKFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLPCELGLAGQNAYK 168
            |||.||||||||||:|||.|:|.||:||.|:|:||||.|.|.|||.|||:.|...:.:|.||.||
Zfish     4 RKFFVGGNWKMNGDKKSIEELANTLNSAKLNPDTEVVCGAPTIYLDYARSKLNPNIDVAAQNCYK 68

  Fly   169 VAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLEE 233
            ||||||||||||||:||.|..||||||||||.:|||||.||.:|..|||..||.|||||||.|:|
Zfish    69 VAKGAFTGEISPAMIKDCGVKWVILGHSERRHVFGESDELIGQKVAHALENGLGVIACIGEKLDE 133

  Fly   234 REAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNISK 298
            ||||.|.:||..|....|..:|||..||:|||||||||||:||:|.||||||..|||||..|:|:
Zfish   134 REAGITEKVVFAQTKFIADNVKDWSKVVLAYEPVWAIGTGKTASPQQAQEVHDKLRQWLKTNVSE 198

  Fly   299 EVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINAR 347
            .|:.|:||.||||||....||||.:.|:||||||||||||||:|||||:
Zfish   199 AVANSVRIIYGGSVTGGTCKELASQKDLDGFLVGGASLKPEFIDIINAK 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpi	NP_788764.1	PTZ00333	102..346	CDD:240365	164/241 (68%)
tpi1b	NP_705954.2	PTZ00333	1..246	CDD:240365	164/241 (68%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580152
Domainoid	1	1.000	323	1.000	Domainoid score	I1185
eggNOG	1	0.900	-	-		E1_COG0149
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2407
OMA	1	1.010	-	-		QHG62471
OrthoDB	1	1.010	-	-		D1272577at2759
OrthoFinder	1	1.000	-	-		FOG0002444
OrthoInspector	1	1.000	-	-		otm24832
orthoMCL	1	0.900	-	-		OOG6_100657
Panther	1	1.100	-	-	LDO	PTHR21139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1539
SonicParanoid	1	1.000	-	-		X1627
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800