DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpi and tpi1a

DIOPT Version :9

Sequence 1:	NP_788764.1	Gene:	Tpi / 43582	FlyBaseID:	FBgn0086355	Length:	348	Species:	Drosophila melanogaster
Sequence 2:	NP_705953.1	Gene:	tpi1a / 192309	ZFINID:	ZDB-GENE-020416-3	Length:	248	Species:	Danio rerio

Alignment Length:	245	Identity:	163/245 - (66%)
Similarity:	191/245 - (77%)	Gaps:	0/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 SRKFCVGGNWKMNGDQKSIAEIAKTLSSAALDPNTEVVIGCPAIYLMYARNLLPCELGLAGQNAY 167
            ||||.||||||||||::|:.|:..||::|:|:..|:||.|.|:|||.|||:.|...:|:|.||.|
Zfish     3 SRKFFVGGNWKMNGDKESLGELIMTLNTASLNDKTDVVCGAPSIYLDYARSKLDQRIGVAAQNCY 67

  Fly   168 KVAKGAFTGEISPAMLKDIGADWVILGHSERRAIFGESDALIAEKAEHALAEGLKVIACIGETLE 232
            ||.||||||||||||:||.|.|||||||||||.:|||||.||.:|..|.|...|.|||||||.||
Zfish    68 KVPKGAFTGEISPAMIKDCGIDWVILGHSERRHVFGESDELIGQKVAHCLESDLGVIACIGEKLE 132

  Fly   233 EREAGKTNEVVARQMCAYAQKIKDWKNVVVAYEPVWAIGTGQTATPDQAQEVHAFLRQWLSDNIS 297
            |||||.|.:||..|....|..:|||..||:|||||||||||:||:|:||||||..||:||..|:|
Zfish   133 EREAGTTEDVVFEQTKVIADNVKDWTRVVLAYEPVWAIGTGKTASPEQAQEVHEKLREWLRANVS 197

  Fly   298 KEVSASLRIQYGGSVTAANAKELAKKPDIDGFLVGGASLKPEFVDIINAR 347
            ..|:.|:||.||||||..|.||||.:.|:|||||||||||||||||||||
Zfish   198 DAVADSVRIIYGGSVTGGNCKELAAQADVDGFLVGGASLKPEFVDIINAR 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpi	NP_788764.1	PTZ00333	102..346	CDD:240365	160/242 (66%)
tpi1a	NP_705953.1	PTZ00333	1..246	CDD:240365	160/242 (66%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580151
Domainoid	1	1.000	323	1.000	Domainoid score	I1185
eggNOG	1	0.900	-	-		E1_COG0149
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H128432
Inparanoid	1	1.050	333	1.000	Inparanoid score	I2407
OMA	1	1.010	-	-		QHG62471
OrthoDB	1	1.010	-	-		D1272577at2759
OrthoFinder	1	1.000	-	-		FOG0002444
OrthoInspector	1	1.000	-	-		otm24832
orthoMCL	1	0.900	-	-		OOG6_100657
Panther	1	1.100	-	-	O	PTHR21139
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1539
SonicParanoid	1	1.000	-	-		X1627
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800