DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppi1 and krt94

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	NP_001070922.1	Gene:	krt94 / 768289	ZFINID:	ZDB-GENE-061027-116	Length:	431	Species:	Danio rerio

Alignment Length:	288	Identity:	52/288 - (18%)
Similarity:	93/288 - (32%)	Gaps:	79/288 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   351 GEGNANRLCQKHSSPRLRQMHISNTRSCVLCGEDVSWLPKVAACPCCG----------YKPVPEF 405
            |:|:..:|.:|.:...|      |.|.       .|:|.||.:.....          |:.....
Zfish    87 GDGDHYQLNEKATMQNL------NDRL-------ASYLDKVRSLEAANATLERQIREYYEKKGPV 138

  Fly   406 KERPYDEQATAQQILLDHLEN----------PVEN---------LSFD-----MGSVEGCSANEE 446
            .||.|.......:.|.|.::|          .::|         :.|:     ..|||...||..
Zfish   139 AERDYSHFWNTIKDLKDKIKNATIHNANILLQIDNSKLAADDFRIKFEHELVMRQSVEADIANLR 203

  Fly   447 HGVPEPT------SEAFEAIVKDYQLLRRSIRESNTKATQSATKNPTAQEGSAQPQDLAKVFTEL 505
            ..:.:.|      ....|.:..:...::::.:|.........|.....:..:|..|||:||..|:
Zfish   204 RLLDQTTLTKADLEMQIEGMQDELAFMKKNHQEDLAALRSQLTGTVNVEVDAAPQQDLSKVLEEI 268

  Fly   506 R---------------DLFNVKAADENQKIQDICAEACALAKSHKKSKNRPASPERTKAGKTDPV 555
            |               |.|..|:|       .:..|.....::.:.:|.:.....||..|    :
Zfish   269 RAHYENIIQKHRREQEDWFKDKSA-------GLSKEVAISTETIQTTKTQITDLRRTLQG----L 322

  Fly   556 EDACETPRKMKKRRPKVKRPYKSRYYSM 583
            |...::...||..........::||.:|
Zfish   323 EIELQSQLSMKAALENSLGDTEARYSAM 350

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622	47/268 (18%)
krt94	NP_001070922.1	Filament	95..404	CDD:278467	49/280 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900