DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppi1 and Krt24

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	NP_083669.1	Gene:	Krt24 / 75706	MGIID:	1922956	Length:	512	Species:	Mus musculus

Alignment Length:	151	Identity:	31/151 - (20%)
Similarity:	56/151 - (37%)	Gaps:	38/151 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 EAECLQRQLAE---GINISVVYLRKEIARGC------------YFPPAAVVSRMINDFDEIVHDA 209
            ||.|.:.::.|   .:....:.|:.::|..|            |....:.:...|:..:|.:...
Mouse   352 EANCARSEVMELKRTVQTLEIELQSQLALKCSLEGTLADTEAGYVAQLSGIQAQISSLEEQLSQI 416

  Fly   210 NVELTCKG----CTVGIMNIRFAMQMRCQTLKEDAVDGRLAGGQERGC-FPNM---NVDLQDLSF 266
            ..|..|:.    |   ::||:..::...:|.:      ||..|...|| :.|:   ||.|.|...
Mouse   417 RAETQCQSAEYEC---LLNIKTRLEQEIETYR------RLLNGDGGGCDYRNLVSKNVVLSDSGS 472

  Fly   267 MSTSSIDPCVGFMPSDTEVAQ 287
            .:....|      ||.|.|.:
Mouse   473 CAGQGKD------PSKTRVTK 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651	31/151 (21%)
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622
Krt24	NP_083669.1	Head	1..140
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..21
		Filament	140..450	CDD:278467	18/106 (17%)
		Coil 1A	141..176
		Linker 1	177..197
		Coil 1B	198..289
		Linker 12	290..312
		Coil 2	313..451		18/107 (17%)
		Tail	452..512		12/42 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900