DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppi1 and Krt10

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	XP_008766313.1	Gene:	Krt10 / 450225	RGDID:	1359092	Length:	599	Species:	Rattus norvegicus

Alignment Length:	206	Identity:	40/206 - (19%)
Similarity:	76/206 - (36%)	Gaps:	58/206 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   354 NANRLCQKHSSPRLRQMHISNTRSCVLCGEDVSWLPKVAACPCCGYKPVPEFKERPYDEQATAQQ 418
            |||.|.|           |.|.|   |..:|                    |:.:..:|.|..|.
  Rat   216 NANVLLQ-----------IDNAR---LAADD--------------------FRLKYENEVALRQS 246

  Fly   419 ILLD--HLENPVENLSFDMGSVEGCSANEEHGVPEPTSEAFEAIVKDYQLLRRSIRESNTKATQS 481
            :..|  .|...::.|:.....:|               ...|::.::...|::: .|...|..|:
  Rat   247 VEADINGLRRVLDELTLSKADLE---------------MQIESLTEELAYLKKN-HEEEMKDLQN 295

  Fly   482 ATKNPTAQEGSAQP-QDLAKVFTELRDLFNVKAADENQKIQDICAEACALAKSHKKSKNRPASPE 545
            .:......|.:|.| .||.::...:|:.:. :.|::|:|    .|||....||.:.:....::.|
  Rat   296 VSTGDVNVEMNAAPGVDLTQLLNNMRNQYE-QLAEKNRK----DAEAWFNEKSKELTTEIDSNIE 355

  Fly   546 RTKAGKTDPVE 556
            :..:.|::..|
  Rat   356 QMSSHKSEITE 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622	35/189 (19%)
Krt10	XP_008766313.1	Filament	144..455	CDD:278467	40/206 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900