DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ppi1 and Krt28

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	XP_006247418.1	Gene:	Krt28 / 360623	RGDID:	1309530	Length:	462	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	43/248 - (17%)
Similarity:	79/248 - (31%)	Gaps:	93/248 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 IVQKLNMPGRDFECQ------DKLQIKANVCRGCKI--CLGSSSINV--NCLP-------LN--- 152
            ::.:|.:...|.|.|      :...:|.|.....|:  |....::||  |..|       ||
  Rat   197 VLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKVLQCAAGGNVNVEMNAAPGVDLTVLLNNMR 261

  Fly   153 -------------PDKTFQMEAECLQRQLAEGINIS------VVYLRKEI--------------- 183
                         .:..||.::..||:|::..:..:      :..|::.:
  Rat   262 AEYEALAEQNRRDAEAWFQEKSATLQQQISNDLGAATSARTELTELKRSLQTLEIELQSLSATKH 326

  Fly   184 --------ARGCYFPPAAVVSRMINDFDEIVHDANVELTCKGCTVG-------IMNIRFAMQMRC 233
                    ..|.|....|.:...|:..:|.:|....|      |.|       :::|:..::...
  Rat   327 SLECTLAETEGNYCSQLAQIQAQISALEEQLHQVRTE------TEGQKLEHEQLLDIKAHLEKEI 385

  Fly   234 QTLKEDAVDGRLAGGQERGCFP----------NMNVDLQDLSFMST--SSIDP 274
            :|.      .||.||.|..|..          |.:.|:...:.:.|  ..|||
  Rat   386 ETY------CRLIGGDENSCSSSKGFESGTSGNSSKDVSKTTLVKTVVEEIDP 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651	43/248 (17%)
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622
Krt28	XP_006247418.1	Filament	83..397	CDD:278467	35/211 (17%)
Krt28	XP_006247418.1	SPEC	178..372	CDD:295325	29/180 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900