DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ppi1 and KRT27

DIOPT Version :9

Sequence 1:NP_733345.2 Gene:Ppi1 / 43581 FlyBaseID:FBgn0051025 Length:998 Species:Drosophila melanogaster
Sequence 2:NP_853515.2 Gene:KRT27 / 342574 HGNCID:30841 Length:459 Species:Homo sapiens


Alignment Length:237 Identity:45/237 - (18%)
Similarity:77/237 - (32%) Gaps:68/237 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   343 SSC-----QKNVLGEGNANRLCQKHSSPRLRQMHISNTRSCVLCGEDV-----SWLPKVAACPCC 397
            :||     .::.|..|| .::..::.:.||.. ::.|.|:......|:     .|..|.....|.
Human    67 ASCAAFTGNEHGLLSGN-EKVTMQNLNDRLAS-YLENVRALEEANADLEQKIKGWYEKFGPGSCR 129

  Fly   398 G-------YKP-VPEFKERPYDEQATAQQILLDH-----------------------LENPVENL 431
            |       |.| :.|.|.:......:...::|.:                       :|..:..|
Human   130 GLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELALHQSVEADINGL 194

  Fly   432 SFDMGSVEGCSANEEHGVPEPTSEAFEAIVKDYQLLRRSIRESNTKATQSATKNPTAQEGSAQP- 495
            ...:..:..|..:.|..: |..||....:.|::        |...||.|.|.......|.:|.| 
Human   195 RRVLDELTLCRTDLEIQL-ETLSEELAYLKKNH--------EEEMKALQCAAGGNVNVEMNAAPG 250

  Fly   496 QDLAKVFTELR---------------DLFNVKAADENQKIQD 522
            .||..:...:|               ..||.|:|...|:|.|
Human   251 VDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISD 292

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ppi1NP_733345.2 DUF4788 108..>294 CDD:292651
DUF4776 371..848 CDD:292622 38/204 (19%)
KRT27NP_853515.2 Head. /evidence=ECO:0000255 1..83 3/15 (20%)
Filament 83..396 CDD:278467 41/221 (19%)
Coil 1A. /evidence=ECO:0000255 84..119 5/35 (14%)
Linker 1. /evidence=ECO:0000255 120..141 4/20 (20%)
Coil 1B. /evidence=ECO:0000255 142..233 13/99 (13%)
SPEC 178..375 CDD:295325 26/124 (21%)
Linker 12. /evidence=ECO:0000255 234..256 7/21 (33%)
Coil 2. /evidence=ECO:0000255 257..395 8/36 (22%)
Tail. /evidence=ECO:0000255 396..459
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 436..459
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_28M49
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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