Protein Alignment Ppi1 and Krt27

DIOPT Version :9

• Sequence 1: NP_733345.2
• Gene: Ppi1 / 43581
• FlyBaseID: FBgn0051025
• Length: 998
• Species: Drosophila melanogaster
• Sequence 2: NP_034796.1
• Gene: Krt27 / 16675
• MGIID: 1339999
• Length: 448
• Species: Mus musculus
• Alignment Length: 474
• Identity: 89/474 - (18%)
• Similarity: 153/474 - (32%)
• Gaps: 153/474 - (32%)

  Fly   210 NVELTCKGCTVGIMNI----RFAMQMRCQTLKEDAVDGRLAGGQERGCFP---------NMNVDL 261
            :|.|:..|..:|..|.    .......|.........|...||...|.|.         |..|.:
Mouse    14 SVRLSSAGAALGAGNACGVPGIGSGFSCAFGGSSLAGGLGMGGASCGAFTANEHGLLSGNEKVTM 78

  Fly   262 QDLSFMSTSSIDPCVGFMPSDTEVAQDSPPCSEDRAQDSFQCQDSPPRLIDMAGPYPVYSCPNVD 326
            |:|:....|.::        :.:..:::....|.:.:|.:          :..||   .||..:|
Mouse    79 QNLNDRLASYLE--------NVQALEEANADLEQKIKDWY----------EKFGP---GSCRGLD 122

  Fly   327 DDCVTFEPPAGP-ATQFSSCQKNVLGEGNANRLCQKHSSP------RLR-----QMH------IS 373
            .|...:.|.... .||..|...:     |||.:.|..::.      |::     .:|      |:
Mouse   123 HDYSRYFPIIDDLRTQIISATAH-----NANIILQNDNARLTADDFRMKYENELALHQSVDADIN 182

  Fly   374 NTR----SCVLC-----------GEDVSWLPK-----VAACPCCG-------------------- 398
            ..|    ...||           .|::::|.|     :.|..|..
Mouse   183 GLRRVLDELTLCRTDLEVQLETLSEELAYLKKNHEEEMQALQCAAGGNVNVEMNAAPGVDLTVLL 247

  Fly   399 ------YKPVPEFKERP----YDEQATAQQILLDHLENPVENLSFDMGSVEGCSANEEHGVPEPT 453
                  |:.:.|...|.    :.|::.:.|          :.:|.|.|:.  .||..|....:.|
Mouse   248 NNMRAEYEALAEQNRRDAEAWFQEKSASLQ----------QQISDDAGAT--TSARNELTEMKRT 300

  Fly   454 SEAFEAIVKDYQLLRRSIRESNTKATQSATKNPTAQ---EGSAQPQDLAKVFT-------ELRDL 508
            .:..|..::....::.|:..|.|: |:.......||   :.||..:.|.:|.|       |...|
Mouse   301 LQTLEIELQSLLAMKHSLECSLTE-TEGNYCTQLAQIQAQISALEEQLHQVRTETEGQKLEYEQL 364

  Fly   509 FNVKAADENQKIQDIC------AEACALAKSHKKSKNRPASPERTKAGKT-----DP-------- 554
            .||||..| ::|:..|      ..:|..||...:..|:.....:|...||     ||
Mouse   365 LNVKAHLE-KEIETYCRLIDGDEGSCVKAKGQGRPGNQTKDSPKTAIVKTVVEELDPRGKVLSSR 428

  Fly   555 ---VEDACETPRKMKKRRP 570
               :|:......|.::|.|
Mouse   429 VHTLEEKSTKVNKTEQRIP 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651	16/96 (17%)
		DUF4776	371..848	CDD:292622	56/288 (19%)
Krt27	NP_034796.1	Head. /evidence=ECO:0000255	1..73		11/58 (19%)
		Filament	73..386	CDD:278467	65/352 (18%)
		Coil 1A. /evidence=ECO:0000255	74..109		5/42 (12%)
		Linker 1. /evidence=ECO:0000255	110..131		6/33 (18%)
		Coil 1B. /evidence=ECO:0000255	132..223		16/95 (17%)
		Linker 12. /evidence=ECO:0000255	224..246		1/21 (5%)
		Coil 2. /evidence=ECO:0000255	247..385		33/151 (22%)
		YlqD	333..>376	CDD:287979	14/43 (33%)
		Tail. /evidence=ECO:0000255	386..448		13/62 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	427..448		4/21 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900