DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppi1 and Krt34

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	NP_081839.1	Gene:	Krt34 / 16672	MGIID:	1309994	Length:	392	Species:	Mus musculus

Alignment Length:	187	Identity:	39/187 - (20%)
Similarity:	62/187 - (33%)	Gaps:	54/187 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKYECKPEP-VEKKEKPVEELMNWDAYYKNRGLVST--RLGSCKADYM---------------- 46
            :.:..|:.|. ||...:.|||.....:...|:.:||:  :|.||:|:.:
Mouse   225 LNETRCQYEALVETNRREVEEWFTTQSEELNKQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQ 289

  Fly    47 HCSTYQEKGNAQEKDKKGKGACCCSSCPVRNREEVYQPRCPAPGQKGKPNRDYMRCFAAKLIVQK 111
            ||.....:....|.:.:.........|.:.|.|          .|.|:...|..|
Mouse   290 HCMRNSLENTLTESEARYSSQLSQVQCLITNVE----------SQLGEIRADLER---------- 334

  Fly   112 LNMPGRDFECQDKLQIKANVCRGCKI-----CLGSSSINVNCLPLNPDKTFQMEAEC 163
                 ::.|.|..|.::|.:  .|:|     .|.|...|   ||.||..|......|
Mouse   335 -----QNQEYQVLLDVRARL--ECEINTYRSLLESEDCN---LPCNPCATTNASGSC 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651	15/61 (25%)
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622
Krt34	NP_081839.1	Head	1..56
		Filament	55..366	CDD:278467	32/167 (19%)
		Coil 1A	57..91
		Linker 1	92..102
		Coil 1B	103..203
		Linker 12	204..219
		Coil 2	220..363		31/164 (19%)
		Tail	364..392		7/21 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900