DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ppi1 and krt98

DIOPT Version :9

Sequence 1:	NP_733345.2	Gene:	Ppi1 / 43581	FlyBaseID:	FBgn0051025	Length:	998	Species:	Drosophila melanogaster
Sequence 2:	XP_005155788.1	Gene:	krt98 / 100124615	ZFINID:	ZDB-GENE-070822-8	Length:	391	Species:	Danio rerio

Alignment Length:	213	Identity:	41/213 - (19%)
Similarity:	83/213 - (38%)	Gaps:	55/213 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   411 DEQATAQQI---LLDHLENPVENLSFDMGSVEGCSANEEHGVPEPTSEAFEAIVKDYQLLRRSIR 472
            |::||.|.:   |..:||.        :.|:|..:...|..:.: ..::.:.:..|:...:.:|:
Zfish    48 DKKATMQNLNTRLASYLEK--------VRSLEKANTELEQKISD-WYDSHDDVTFDHTNFQDTIQ 103

  Fly   473 ----ESNTKATQSAT-------------------KNPTA--QEGSAQPQDLAKVFTELRDLFNVK 512
                |.||::..:|.                   :|..|  :|..|...:|.|:..|    |::.
Zfish   104 DLRNEFNTRSQDNAKLILEVDNAKLAADDFKRKYENELAMRREIEADTGNLRKILDE----FSLS 164

  Fly   513 AADENQKIQDICAEACALAKSHKK------------SKNRPASPERTKAGKTDPVEDACETPRKM 565
            .:|...:|:.:..|...|.|:||:            :.:..|:|........|.:....||  ..
Zfish   165 RSDLELQIEALKEEFIVLKKNHKENITLTIETGGQVNVSVDAAPSMDLNQAIDEIRQHYET--VT 227

  Fly   566 KKRRPKVKRPYKSRYYSM 583
            :|.|.:::..|:|:...|
Zfish   228 QKNREELESWYESKMAPM 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ppi1	NP_733345.2	DUF4788	108..>294	CDD:292651
Ppi1	NP_733345.2	DUF4776	371..848	CDD:292622	41/213 (19%)
krt98	XP_005155788.1	Filament	50..356	CDD:278467	40/211 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28M49
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900