DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-A and RAD51

DIOPT Version :9

Sequence 1:	NP_524583.1	Gene:	spn-A / 43577	FlyBaseID:	FBgn0003479	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_568402.1	Gene:	RAD51 / 832208	AraportID:	AT5G20850	Length:	342	Species:	Arabidopsis thaliana

Alignment Length:	340	Identity:	197/340 - (57%)
Similarity:	254/340 - (74%)	Gaps:	6/340 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKLTN---VQAQQEEEEEEGPLSVTKLIGGSITAKDIKLLQQASLHTVESVANATKKQLMAIPG 62
            ||:..|   ||.|.:||.:.||..|.:|....|.:.|:|.|:.|.|.|||.||...:|.|:.|.|
plant     4 MEQRRNQNAVQQQDDEETQHGPFPVEQLQAAGIASVDVKKLRDAGLCTVEGVAYTPRKDLLQIKG 68

  Fly    63 LGGGKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITEIFGEFR 127
            :...||::|:..|:|||||||.||...:..|.:::|:::||:||||:|.||||||||||::||||
plant    69 ISDAKVDKIVEAASKLVPLGFTSASQLHAQRQEIIQITSGSRELDKVLEGGIETGSITELYGEFR 133

  Fly   128 CGKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPERLAAIAQRYKLNESEVLDNVAFTRAH 192
            .|||||||||.||||||:.|.|||||.||||.|.||||:||..||.|:.||.::||:|||:.||:
plant   134 SGKTQLCHTLCVTCQLPMDQGGGEGKAMYIDAEGTFRPQRLLQIADRFGLNGADVLENVAYARAY 198

  Fly   193 NSDQQTKLIQMAAGMLFESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFG 257
            |:|.|::|:..||.|:.|:|:||||||||.||||:|:.|||||:|||.||..|||.||:||||||
plant   199 NTDHQSRLLLEAASMMIETRFALLIVDSATALYRTDFSGRGELSARQMHLAKFLRSLQKLADEFG 263

  Fly   258 VAVVITNQVTASLDGAPGMFDAK--KPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESE 320
            |||||||||.|.:||: .:|...  |||||:||||::||||.||||:.|.||||:..||||||:|
plant   264 VAVVITNQVVAQVDGS-ALFAGPQFKPIGGNIMAHATTTRLALRKGRAEERICKVISSPCLPEAE 327

  Fly   321 AMFAILPDGIGDARE 335
            |.|.|..:|:.|.::
plant   328 ARFQISTEGVTDCKD 342

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	187/314 (60%)
		HHH_5	30..77	CDD:291205	19/46 (41%)
		Rad51_DMC1_radA	99..331	CDD:238543	154/233 (66%)
RAD51	NP_568402.1	PLN03186	1..342	CDD:178728	197/338 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	325	1.000	Domainoid score	I269
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2155
Inparanoid	1	1.050	386	1.000	Inparanoid score	I515
OMA	1	1.010	-	-		QHG62165
OrthoDB	1	1.010	-	-		D877394at2759
OrthoFinder	1	1.000	-	-		FOG0001571
OrthoInspector	1	1.000	-	-		oto3920
orthoMCL	1	0.900	-	-		OOG6_100483
Panther	1	1.100	-	-	LDO	PTHR22942
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3765
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840