DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-A and DMC1

DIOPT Version :9

Sequence 1:	NP_524583.1	Gene:	spn-A / 43577	FlyBaseID:	FBgn0003479	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_188928.2	Gene:	DMC1 / 821860	AraportID:	AT3G22880	Length:	344	Species:	Arabidopsis thaliana

Alignment Length:	339	Identity:	165/339 - (48%)
Similarity:	221/339 - (65%)	Gaps:	7/339 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 EKLTNVQ-AQQEEEEEEGPL--SVTKLIGGSITAKDIKLLQQASLHTVESVANATKKQLMAIPGL 63
            |:.:.:| .::||.:|:..|  .:.|||...|.|.|:|.||:|.:||...:...|||.|..|.||
plant     8 EETSQMQLVEREENDEDEDLFEMIDKLIAQGINAGDVKKLQEAGIHTCNGLMMHTKKNLTGIKGL 72

  Fly    64 GGGKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITEIFGEFRC 128
            ...||::|...|.|:|..|:::.......|..||:::||.:.||.||||||||.:|||.|||||.
plant    73 SEAKVDKICEAAEKIVNFGYMTGSDALIKRKSVVKITTGCQALDDLLGGGIETSAITEAFGEFRS 137

  Fly   129 GKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPERLAAIAQRYKLNESEVLDNVAFTRAHN 193
            |||||.|||.||.|||.:.|||.||..|||||.||||:|:..||:|:.::...||||:.:.||:.
plant   138 GKTQLAHTLCVTTQLPTNMKGGNGKVAYIDTEGTFRPDRIVPIAERFGMDPGAVLDNIIYARAYT 202

  Fly   194 SDQQTKLIQMAAGMLFESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFGV 258
            .:.|..|:...|..:.|..:.:|||||.:||:|.|:.||||||.||..|...|..|.::|:||.|
plant   203 YEHQYNLLLGLAAKMSEEPFRILIVDSIIALFRVDFTGRGELADRQQKLAQMLSRLIKIAEEFNV 267

  Fly   259 AVVITNQVTASLDGAPGMF--DAKKPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESEA 321
            ||.:||||.|  |...|||  |.|||.|||::||::|.||..|||||:||:||:||:|.|.|:||
plant   268 AVYMTNQVIA--DPGGGMFISDPKKPAGGHVLAHAATIRLLFRKGKGDTRVCKVYDAPNLAEAEA 330

  Fly   322 MFAILPDGIGDARE 335
            .|.|...||.||::
plant   331 SFQITQGGIADAKD 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	159/314 (51%)
		HHH_5	30..77	CDD:291205	20/46 (43%)
		Rad51_DMC1_radA	99..331	CDD:238543	127/233 (55%)
DMC1	NP_188928.2	PLN03187	1..344	CDD:215620	165/337 (49%)
		HHH_5	38..86	CDD:291205	20/47 (43%)
		Rad51_DMC1_radA	108..339	CDD:238543	126/232 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62165
OrthoDB	1	1.010	-	-		D877394at2759
OrthoFinder	1	1.000	-	-		FOG0001571
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100483
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.730