Protein Alignment spn-A and XRCC3

DIOPT Version :9

• Sequence 1: NP_524583.1
• Gene: spn-A / 43577
• FlyBaseID: FBgn0003479
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: NP_001093588.1
• Gene: XRCC3 / 7517
• HGNCID: 12830
• Length: 346
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 88/331 - (26%)
• Similarity: 143/331 - (43%)
• Gaps: 41/331 - (12%)

  Fly    35 IKLLQQASLHTVESVANATKKQLMAIPGLGGGKVEQIITEAN-KLVPLGFLSARTFYQMR----A 94
            |..:::|.|.:|:.|.:.:...|..:..|...:|..::..|: .|.....|:|...:|.:    .
Human    13 IAAIKKAKLKSVKEVLHFSGPDLKRLTNLSSPEVWHLLRTASLHLRGSSILTALQLHQQKERFPT 77

  Fly    95 DVVQLSTGSKELDKLLGGGIETGSITEIFGEFRCGKTQLCHTLAVTCQLPISQKGGEGKCMYIDT 159
            ...:||.|...||.||.||:....|||:.|....|||||...|.:..|.|....|.|...:||.|
Human    78 QHQRLSLGCPVLDALLRGGLPLDGITELAGRSSAGKTQLALQLCLAVQFPRQHGGLEAGAVYICT 142

  Fly   160 ENTFRPERLAAI-AQRYKLN---ESEVLDNVAFTR----AHNSDQQTKL--------IQMAAGML 208
            |:.|..:||..: ||:.:|.   ..|:|..:.|..    .|.:|..|.|        :.::.||.
Human   143 EDAFPHKRLQQLMAQQPRLRTDVPGELLQKLRFGSQIFIEHVADVDTLLECVNKKVPVLLSRGMA 207

  Fly   209 FESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFGVAVVITNQVTASLD-- 271
                 .|:::||..|.:|.::..:.. |.|..||......|:.|:..|...|:..||||.:::
Human   208 -----RLVVIDSVAAPFRCEFDSQAS-APRARHLQSLGATLRELSSAFQSPVLCINQVTEAMEEQ 266

  Fly   272 ----GAPGMFDAK-KPIGGHIMAHSSTTRLYLRKGKGE-------TRICKIYDSPCLPESEAMFA 324
                |..|.:|.: .|..|...|:....||...:.:.|       .|..::..:|.||.|...:.
Human   267 GAAHGPLGFWDERVSPALGITWANQLLVRLLADRLREEEAALGCPARTLRVLSAPHLPPSSCSYT 331

  Fly   325 ILPDGI 330
            |..:|:
Human   332 ISAEGV 337

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	88/331 (27%)
		HHH_5	30..77	CDD:291205	9/42 (21%)
		Rad51_DMC1_radA	99..331	CDD:238543	75/262 (29%)
XRCC3	NP_001093588.1	Rad51_DMC1_radA	82..338	CDD:238543	75/262 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810