Protein Alignment spn-A and RAD51C

DIOPT Version :10

• Sequence 1: NP_524583.1
• Gene: spn-A / 43577
• FlyBaseID: FBgn0003479
• Length: 336
• Species: Drosophila melanogaster
• Sequence 2: XP_006722064.1
• Gene: RAD51C / 5889
• HGNCID: 9820
• Length: 377
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 97/363 - (26%)
• Similarity: 149/363 - (41%)
• Gaps: 72/363 - (19%)

  Fly     3 KLTNVQAQQEEE-EEEGPLSVTKLIGGSITAKDIKLLQ----------QASLHTVESVANATKKQ 56
            ||.:...|..|| .|..|..::|.:|.| .|:.::.||          .....|.||....|..:
Human    26 KLVSAGFQTAEELLEVKPSELSKEVGIS-KAEALETLQIIRRECLTNKPRYAGTSESHKKCTALE 89

  Fly    57 LMAIPGLGGGKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITE 121
            |:          ||..|:       ||               :.|....||.:||||:.....||
Human    90 LL----------EQEHTQ-------GF---------------IITFCSALDDILGGGVPLMKTTE 122

  Fly   122 IFGEFRCGKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPER-----------LAAIAQRY 175
            |.|....||||||..|||..|:|....|..|:.::||||.:|..:|           |..||:::
Human   123 ICGAPGVGKTQLCMQLAVDVQIPECFGGVAGEAVFIDTEGSFMVDRVVDLATACIQHLQLIAEKH 187

  Fly   176 KLNE----------SEVLDNVAFTRAHNSDQQTKLIQMAAGMLFE-SRYALLIVDSAMALYRSDY 229
            |..|          ..:|.::.:.|..:..:....:.:....|.| |:..|:|||.....:|.|.
Human   188 KGEEHRKALEDFTLDNILSHIYYFRCRDYTELLAQVYLLPDFLSEHSKVRLVIVDGIAFPFRHDL 252

  Fly   230 IGRGELAARQNHLGLFLRMLQRLADEFGVAVVITNQVTASLDGAPGMFDAKKPIGGHIMAHSSTT 294
               .:|:.|...|....:.:..||:...:||::|||:|..:|....:.   .|..|....|::|.
Human   253 ---DDLSLRTRLLNGLAQQMISLANNHRLAVILTNQMTTKIDRNQALL---VPALGESWGHAATI 311

  Fly   295 RLYLRKGKGETRICKIYDSPCLPESEAMFAILPDGIGD 332
            ||.....:.::|:..:|.||...|...:|.|.|.|..|
Human   312 RLIFHWDRKQSRLATLYKSPSQKECTVLFQIKPQGFRD 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	90/343 (26%)
RAD51C	XP_006722064.1	Rad51C	118..331	CDD:410900	59/218 (27%)