DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-A and rad51

DIOPT Version :9

Sequence 1:	NP_524583.1	Gene:	spn-A / 43577	FlyBaseID:	FBgn0003479	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_001016393.1	Gene:	rad51 / 549147	XenbaseID:	XB-GENE-1016881	Length:	336	Species:	Xenopus tropicalis

Alignment Length:	337	Identity:	226/337 - (67%)
Similarity:	273/337 - (81%)	Gaps:	3/337 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEKLTNVQAQQEEEEEEGPLSVTKLIGGSITAKDIKLLQQASLHTVESVANATKKQLMAIPGLGG 65
            |....:.:|:..|||..||.::::|....|.|.|:|.|::|..||||:||.|.||:|:.|.|:..
Frog     1 MAMQAHYEAEATEEENFGPQAISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISE 65

  Fly    66 GKVEQIITEANKLVPLGFLSARTFYQMRADVVQLSTGSKELDKLLGGGIETGSITEIFGEFRCGK 130
            .|.|:|:.||.||||:||.:|..|:|.|::::|:|||||||||||.||||||||||:|||||.||
Frog    66 AKAEKILAEAAKLVPMGFTTATEFHQRRSEIIQISTGSKELDKLLQGGIETGSITEMFGEFRTGK 130

  Fly   131 TQLCHTLAVTCQLPISQKGGEGKCMYIDTENTFRPERLAAIAQRYKLNESEVLDNVAFTRAHNSD 195
            |||||||||||||||.:.|||||.||||||.|||||||.|:|:||.|:.|:||||||:.||.|:|
Frog   131 TQLCHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTD 195

  Fly   196 QQTKLIQMAAGMLFESRYALLIVDSAMALYRSDYIGRGELAARQNHLGLFLRMLQRLADEFGVAV 260
            .||:|:..|:.|:.||||||||||||.||||:||.|||||:|||.||..|||||.||||||||||
Frog   196 HQTQLLYQASAMMAESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAV 260

  Fly   261 VITNQVTASLDGAPGMF--DAKKPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESEAMF 323
            ||||||.|.:||| .||  |.||||||:|:||:||||||||||:||||||||||||||||:||||
Frog   261 VITNQVVAQVDGA-AMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMF 324

  Fly   324 AILPDGIGDARE 335
            ||..||:|||::
Frog   325 AINADGVGDAKD 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	219/314 (70%)
		HHH_5	30..77	CDD:291205	23/46 (50%)
		Rad51_DMC1_radA	99..331	CDD:238543	181/233 (78%)
rad51	NP_001016393.1	recomb_RAD51	22..336	CDD:274048	219/314 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	377	1.000	Domainoid score	I850
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H2155
Inparanoid	1	1.050	443	1.000	Inparanoid score	I1602
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D357659at33208
OrthoFinder	1	1.000	-	-		FOG0001571
OrthoInspector	1	1.000	-	-		oto102893
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3765
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.060