DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spn-A and spn-D

DIOPT Version :9

Sequence 1:	NP_524583.1	Gene:	spn-A / 43577	FlyBaseID:	FBgn0003479	Length:	336	Species:	Drosophila melanogaster
Sequence 2:	NP_733200.1	Gene:	spn-D / 318579	FlyBaseID:	FBgn0003482	Length:	270	Species:	Drosophila melanogaster

Alignment Length:	243	Identity:	69/243 - (28%)
Similarity:	104/243 - (42%)	Gaps:	37/243 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    98 QLSTGSKELDKLLGGGIETGSITEIFGEFRCGKTQLCHTLAVTCQLPISQKGGEGKCMYIDTENT 162
            ::.||.|.||...||||..|.:.|:.|....||||:|..|.:..|:|.:..|.||..::|||...
  Fly    45 KILTGKKALDTHFGGGISLGHLVELIGNSGTGKTQMCLQLCLNVQIPKAAGGLEGSALFIDTRQD 109

  Fly   163 FRPERLAAIAQRYKLNESEVLDNVAFTRAHNSDQQ------TKLIQMAAGMLFESRY-------A 214
            |.|:||..:|.:.   |.:....|...:||...|:      .||.|:.|.:|...|:       .
  Fly   110 FHPDRLMGLALKL---ERQYAHRVPEFKAHKMLQKIHYVRCPKLDQLMATVLSCHRHLVDHPDIK 171

  Fly   215 LLIVDSAMALYR--SDYIGRGELAARQNHLGLFLRMLQRLADEFGVAVVITNQVT-----ASLDG 272
            |:::||.....|  .|...|.|:..   .|...:|.|||   :..:..|.||.:|     .....
  Fly   172 LIVIDSLAFTLRMLEDGAHRYEMLL---ELHESMRRLQR---QHELTWVFTNVLTHRYVKQKFQV 230

  Fly   273 APGMFDAKKPIGGHIMAHSSTTRLYLRKGKGETRICKIYDSPCLPESE 320
            .|.:.|....:....:..|.::.|:|.|....:|:.|        |||
  Fly   231 EPALGDLHSHLINERIWFSGSSELHLGKSWRTSRLIK--------ESE 270

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spn-A	NP_524583.1	recomb_RAD51	22..335	CDD:274048	69/243 (28%)
		HHH_5	30..77	CDD:291205
		Rad51_DMC1_radA	99..331	CDD:238543	69/242 (29%)
spn-D	NP_733200.1	P-loop_NTPase	46..249	CDD:304359	60/211 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0468
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22942
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840