DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7943 and slc25a51b

DIOPT Version :9

Sequence 1:	NP_651766.1	Gene:	CG7943 / 43574	FlyBaseID:	FBgn0039741	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_001373173.1	Gene:	slc25a51b / 556422	ZFINID:	ZDB-GENE-140328-2	Length:	303	Species:	Danio rerio

Alignment Length:	307	Identity:	132/307 - (42%)
Similarity:	176/307 - (57%)	Gaps:	22/307 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 SGRAHSPHGDGEAGKLLHGSVFSKRFFGSFQWEEFACGCGAAFVNIAVTYPIYKMIFRQMLHGVP 87
            |..|..|.|. ..|..|.|:....|      .:.:.||..|||.||.||:||.|::|||.||||.
Zfish     9 SDSARQPQGK-LGGHALIGANLGAR------GKHYVCGSLAAFTNIIVTFPIQKVLFRQQLHGVR 66

  Fly    88 ITSAFAQLRHEGLGFLYRGMLPPLAQKTISLSIMFGVFDGTRRYLVEDYRLNDYGAKVL-----A 147
            .|.|..||:.|||..||||:||||.|||.:::||||:::...|.|:...|.:  ||..|     |
Zfish    67 ATEAVGQLQREGLRHLYRGLLPPLLQKTTTVAIMFGLYEDFSRLLLRHARSS--GAPELVTRSAA 129

  Fly   148 AVVAGSAESILLPFERVQTLLADSKFHQHFSNTQNAFRYVVSHHGYRELYRGLEPVFWRNGLSNA 212
            |.:||:||:.|.|||||||||.|.:.:..|:||.:.||.::..:|.||.||||.||..|||.||.
Zfish   130 AALAGTAEAALTPFERVQTLLQDHRHNGRFNNTAHTFRTLLRDYGVRECYRGLVPVLLRNGPSNV 194

  Fly   213 LFFVLREEASVRLPKRKSVSTRTVQEFIAGAVIGASISTIFYPLNVIKVSLQSEMGQRSEGSWQA 277
            |||.||......||..:|.......:|:.|.::||::..:||||||:|...|:::|    |.:..
Zfish   195 LFFGLRGPIKQWLPDARSRMGNMANDFVCGGLLGAALGIMFYPLNVVKSRAQAQVG----GKFVP 255

  Fly   278 CKRIYV----ERDRRIGNFYRGCPFNTGRSFISWGIMNTAYENLKKL 320
            |..|.:    ||...|...:||...|..||.:||||:|..||.|.|:
Zfish   256 CHTILMTVWRERGGSIVLLFRGATLNYHRSLLSWGIINATYELLLKV 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7943	NP_651766.1	Mito_carr	54..136	CDD:278578	43/81 (53%)
		Mito_carr	141..229	CDD:278578	46/92 (50%)
		Mito_carr	235..322	CDD:278578	33/90 (37%)
slc25a51b	NP_001373173.1	Mito_carr	33..114	CDD:395101	43/80 (54%)
		Mito_carr	<141..209	CDD:395101	35/67 (52%)
		Mito_carr	216..303	CDD:395101	33/91 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	92	1.000	Domainoid score	I7591
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H88487
Inparanoid	1	1.050	224	1.000	Inparanoid score	I3494
OMA	1	1.010	-	-		QHG59392
OrthoDB	1	1.010	-	-		D503015at33208
OrthoFinder	1	1.000	-	-		FOG0004171
OrthoInspector	1	1.000	-	-		otm24898
orthoMCL	1	0.900	-	-		OOG6_107186
Panther	1	1.100	-	-	LDO	PTHR46131
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3422
SonicParanoid	1	1.000	-	-		X4548
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	14.010