DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG7943 and SLC25A53

DIOPT Version :10

Sequence 1:NP_651766.1 Gene:CG7943 / 43574 FlyBaseID:FBgn0039741 Length:332 Species:Drosophila melanogaster
Sequence 2:NP_001012773.2 Gene:SLC25A53 / 401612 HGNCID:31894 Length:307 Species:Homo sapiens


Alignment Length:288 Identity:89/288 - (30%)
Similarity:148/288 - (51%) Gaps:31/288 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 GSFQW--EEFACGCGAAFVNIAVTYPIYKMIFRQMLHGVPITSAFAQLRHEGLGFLYRGMLPPLA 112
            |...|  :.:|.|..:.|::..:|:||||::|||.:|.:.::.|..||.|||..:.|||:.|||.
Human    22 GKKSWHSQAYALGAVSNFMSTFLTFPIYKVVFRQQIHAMAVSEAVRQLWHEGPQYFYRGIYPPLL 86

  Fly   113 QKTISLSIMFGVFDGTRRYL--VEDYRLNDYGAKVLAAVVAGSAESILL-PFERVQTLLADSKFH 174
            .||:..:::||.:|....:|  |..:.|   |.:..|.:::|..|::.| ||||||.:|.|.:..
Human    87 SKTLQGTLLFGTYDSLLCFLSPVGPHTL---GHRWAAGLMSGVVEAVALSPFERVQNVLQDGRKQ 148

  Fly   175 QHFSNTQNAFRYVVSHH-------GYRELYRGLEPVFWRNGLSNALFFVLREE-----ASVRLPK 227
            ..|.:|.:..:...|:.       ||   |||..||..||.|.:||:|..::.     |...|| 
Human   149 ARFPSTFSILKEFNSYGLWGRLSLGY---YRGFWPVLARNSLGSALYFSFKDPIQDGLAEQGLP- 209

  Fly   228 RKSVSTRTVQEFIAGAVIGASISTIFYPLNVIKVSLQSEMG-QRSEGSWQACKRIYVERDRRIGN 291
                  ..|...::|:|.|.....:.|||.|:..::||.:| |.....|.:.:.::..|.|::..
Human   210 ------HWVPALVSGSVNGTITCLVLYPLIVLVANMQSHIGWQNMPSLWASAQDVWNTRGRKLLL 268

  Fly   292 FYRGCPFNTGRSFISWGIMNTAYENLKK 319
            .|||......||.::||:....::.|::
Human   269 IYRGGSLVILRSSVTWGLTTAIHDFLQR 296

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG7943NP_651766.1 Mito_carr 54..136 CDD:395101 32/85 (38%)
Mito_carr 141..229 CDD:395101 32/100 (32%)
Mito_carr 235..322 CDD:395101 23/86 (27%)