DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7943 and Dic3

DIOPT Version :9

Sequence 1:	NP_651766.1	Gene:	CG7943 / 43574	FlyBaseID:	FBgn0039741	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	NP_610344.2	Gene:	Dic3 / 35763	FlyBaseID:	FBgn0033248	Length:	287	Species:	Drosophila melanogaster

Alignment Length:	173	Identity:	38/173 - (21%)
Similarity:	63/173 - (36%)	Gaps:	42/173 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 YKMIFRQMLHGVPITSAFAQLRHEGLGFLYRGMLPPLAQKTI--------------SLSIMFGVF 125
            ||.:|         ...|...:.||:..|:||.:|.:::..:              .|.|..|..
  Fly   139 YKHVF---------DGLFRIYKEEGVSSLFRGTVPAVSRAVLLTIGTNAAYDQVKQMLKIATGAG 194

  Fly   126 DGTRRYLVEDYRLNDYGAKVLAAVVAGS-AESILLPFERVQTLLADSKFHQHFSNTQNAFRYVVS 189
            :|...:..             .:.:||. |..|..|.:.::|...::: ...||....|| ...:
  Fly   195 EGVPLHFA-------------TSTIAGCIAVVITQPLDVIKTTFMNAQ-PGEFSGIGGAF-LSTA 244

  Fly   190 HHGYRELYRGLEPVFWRNGLSNALFFVLREEASVR---LPKRK 229
            ..|....|:|..|...|...:..:.|||.|:|.:|   ||..|
  Fly   245 KQGPLAFYKGFIPALIRVSPNTIITFVLYEQARMRFGYLPPDK 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7943	NP_651766.1	Mito_carr	54..136	CDD:278578	14/74 (19%)
		Mito_carr	141..229	CDD:278578	23/91 (25%)
		Mito_carr	235..322	CDD:278578
Dic3	NP_610344.2	PTZ00169	15..275	CDD:240302	32/159 (20%)
		Mito_carr	15..91	CDD:278578
		Mito_carr	93..187	CDD:278578	10/56 (18%)
		Mito_carr	200..281	CDD:278578	21/95 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930