Protein Alignment CG7943 and SLC25A6

DIOPT Version :10

• Sequence 1: NP_651766.1
• Gene: CG7943 / 43574
• FlyBaseID: FBgn0039741
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_001627.2
• Gene: SLC25A6 / 293
• HGNCID: 10992
• Length: 298
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 66/308 - (21%)
• Similarity: 121/308 - (39%)
• Gaps: 53/308 - (17%)

  Fly    51 SFQWEEFACGCGAAFVNIAVTYPIYKM-IFRQMLHGVPITSAFAQL-----------RHEGLGFL 103
            ||..:..|.|..||....||. ||.:: :..|:.|.....:|..|.           :.:|:...
Human     7 SFAKDFLAGGIAAAISKTAVA-PIERVKLLLQVQHASKQIAADKQYKGIVDCIVRIPKEQGVLSF 70

  Fly   104 YRGMLPPLAQKTISLSIMFGVFDGTRRYLV-------EDYRLNDYGAKVLAAVVAGSAESI--LL 159
            :||.|..:.:...:.::.|...|..::..:       :.:|   |.|..||:..|..|.|:  :.
Human    71 WRGNLANVIRYFPTQALNFAFKDKYKQIFLGGVDKHTQFWR---YFAGNLASGGAAGATSLCFVY 132

  Fly   160 PFERVQTLLADSKFHQHFSNTQNAFR-------YVVSHHGYRELYRGLEPVFWRNGLSNALFFVL 217
            |.:..:|.||.....   |.|:..||       .:....|.|.||:|.........:..|.:|.:
Human   133 PLDFARTRLAADVGK---SGTEREFRGLGDCLVKITKSDGIRGLYQGFSVSVQGIIIYRAAYFGV 194

  Fly   218 REEASVRLPKRKSVSTRTVQEFIAGAVIGASISTIFYPLNVIKVSLQSEMGQRS-----EGSWQA 277
            .:.|...||..|  :|..|..::....:.|....:.||.:.::..:..:.|::.     .|:...
Human   195 YDTAKGMLPDPK--NTHIVVSWMIAQTVTAVAGVVSYPFDTVRRRMMMQSGRKGADIMYTGTVDC 257

  Fly   278 CKRIYVERDRRIGNFYRGCPFNT----GRSFISWGIMNTAYENLKKLM 321
            .::|:  ||.....|::|...|.    |.:|:.     ..|:.|||::
Human   258 WRKIF--RDEGGKAFFKGAWSNVLRGMGGAFVL-----VLYDELKKVI 298

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7943	NP_651766.1	Mito_carr	54..136	CDD:395101	18/100 (18%)
		Mito_carr	141..229	CDD:395101	25/96 (26%)
		Mito_carr	235..322	CDD:395101	18/96 (19%)
SLC25A6	NP_001627.2	PTZ00169	3..298	CDD:240302	66/306 (22%)
		Solcar 1	6..98		20/91 (22%)
		Solcar 2	111..201		24/95 (25%)
		Solcar 3	212..297		16/91 (18%)
		Important for transport activity. /evidence=ECO:0000250|UniProtKB:P12235	235..240		0/4 (0%)
		Nucleotide carrier signature motif. /evidence=ECO:0000250|UniProtKB:P02722	235..240		0/4 (0%)