Protein Alignment CG7943 and SLC25A45

DIOPT Version :10

• Sequence 1: NP_651766.1
• Gene: CG7943 / 43574
• FlyBaseID: FBgn0039741
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_872362.4
• Gene: SLC25A45 / 283130
• HGNCID: 27442
• Length: 288
• Species: Homo sapiens
• Alignment Length: 295
• Identity: 67/295 - (22%)
• Similarity: 119/295 - (40%)
• Gaps: 47/295 - (15%)

  Fly    55 EEFACGCGAAFVNIAVTYPIYKMIFR---QMLHGVPITSAFAQLRHEGLGFLYRGMLPPLAQKTI 116
            |||..|..:..:.:.:.:|...:..|   |..:...:.......|||.|...::||..|:|...:
Human     4 EEFVAGWISGALGLVLGHPFDTVKVRLQTQTTYRGIVDCMVKIYRHESLLGFFKGMSFPIASIAV 68

  Fly   117 SLSIMFGVFDGTRRYLV----EDYRLN--DYGAKVLAAVVAGSAES-ILLPFERVQTLLADS--- 171
            ..|::|||:..|...|.    ::.|..  .|....||....|..:: .|.||:.::..|.:.
Human    69 VNSVLFGVYSNTLLVLTATSHQERRAQPPSYMHIFLAGCTGGFLQAYCLAPFDLIKVRLQNQTEP 133

  Fly   172 ---------KFHQHFSNTQNAFRYVVSHHGYRELYRGLEPVFWRNGLSNALFFVLREEASVR-LP 226
                     ::........:.||    ..|.|.|:||...:..|:..:..::|:..|....: .|
Human   134 RAQPGSPPPRYQGPVHCAASIFR----EEGPRGLFRGAWALTLRDTPTVGIYFITYEGLCRQYTP 194

  Fly   227 KRKSVSTRTVQEFIAGAVIGASISTIFYPLNVIKVSLQSEMGQRSEGSWQACKRIYVE------- 284
            :.::.|:.||  .:||...|.:......||::||..:|.: |.|        :|:|..
Human   195 EGQNPSSATV--LVAGGFAGIASWVAATPLDMIKSRMQMD-GLR--------RRVYQGMLDCMVS 248

  Fly   285 --RDRRIGNFYRGCPFNTGRSFISWGIMNTAYENL 317
              |...:|.|:||...|:.|:|....:...:||.|
Human   249 SIRQEGLGVFFRGVTINSARAFPVNAVTFLSYEYL 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7943	NP_651766.1	Mito_carr	54..136	CDD:395101	21/87 (24%)
		Mito_carr	141..229	CDD:395101	19/101 (19%)
		Mito_carr	235..322	CDD:395101	25/92 (27%)
SLC25A45	NP_872362.4	Solcar 1	1..83		20/78 (26%)
		Mito_carr	2..77	CDD:395101	18/72 (25%)
		Mito_carr	95..186	CDD:395101	17/94 (18%)
		Solcar 2	97..191		18/97 (19%)
		Mito_carr	197..288	CDD:395101	26/98 (27%)
		Solcar 3	199..286		26/96 (27%)