DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7943 and slc25a53

DIOPT Version :9

Sequence 1:	NP_651766.1	Gene:	CG7943 / 43574	FlyBaseID:	FBgn0039741	Length:	332	Species:	Drosophila melanogaster
Sequence 2:	XP_002940455.1	Gene:	slc25a53 / 100489481	XenbaseID:	XB-GENE-6045975	Length:	283	Species:	Xenopus tropicalis

Alignment Length:	296	Identity:	88/296 - (29%)
Similarity:	149/296 - (50%)	Gaps:	45/296 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 HGSVFSKRFFGSFQWEEFACGCGAAFVNIAVTYPIYKMIFRQMLHGVPITSAFAQLRHEGLGFLY 104
            |||.:|             .|..:.|::..:|:||||.||||.||.:.|..|..||..||...||
Frog    13 HGSSYS-------------VGATSTFLSTVLTFPIYKTIFRQQLHTLTIREASQQLLKEGFAHLY 64

  Fly   105 RGMLPPLAQKTISLSIMFGVFDGTRRYLVEDYRLNDYGAKVLAAVVAGSAESILL-PFERVQTLL 168
            ||:.|||..||:..:::||.....::.|..:.::..:. :.|:.:::|:.|::|| ||||:|.:|
Frog    65 RGLAPPLVAKTVQGTLLFGTQATFQKSLSGNGKVGHWD-RCLSGLMSGALEAVLLVPFERIQNIL 128

  Fly   169 ADSKFHQHFS------------NTQNAFRYVVSHHGYRELYRGLEPVFWRNGLSNALFFVLREEA 221
            .|.:.:..|.            :|||.|.:        .||||...:..||.|.:||:|..:|
Frog   129 QDGRNNARFPSANSILQEFQSYSTQNRFTF--------GLYRGFSVILARNALGSALYFSFKE-- 183

  Fly   222 SVRLPKRKSVS----TRTVQEFIAGAVIGASISTIFYPLNVIKVSLQSEMGQRSEGSWQACKRIY 282
                |.|.::|    ...|...::|:|.||..|.|.|||:|:..::|:.:|:....:.:..:.::
Frog   184 ----PLRDALSLDGVPGWVPSLVSGSVNGALTSLILYPLSVLVSNMQAGVGKELPKTREVARAVW 244

  Fly   283 VERDRRIGNFYRGCPFNTGRSFISWGIMNTAYENLK 318
            ::....:...|||......||.|:||:....::.|:
Frog   245 LQCGGNVSLLYRGASLIILRSCITWGVTTAIHDVLR 280

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7943	NP_651766.1	Mito_carr	54..136	CDD:278578	31/81 (38%)
		Mito_carr	141..229	CDD:278578	29/100 (29%)
		Mito_carr	235..322	CDD:278578	22/84 (26%)
slc25a53	XP_002940455.1	Mito_carr	20..94	CDD:365909	31/73 (42%)
		Mito_carr	101..189	CDD:365909	30/102 (29%)
		Mito_carr	195..280	CDD:365909	21/84 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	67	1.000	Domainoid score	I9694
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4455
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D503015at33208
OrthoFinder	1	1.000	-	-		FOG0004171
OrthoInspector	1	1.000	-	-		oto104455
Panther	1	1.100	-	-	O	PTHR46131
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.070