DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-delta and ZNF665

DIOPT Version :9

Sequence 1:NP_524581.1 Gene:Sry-delta / 43572 FlyBaseID:FBgn0003512 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_001340387.1 Gene:ZNF665 / 79788 HGNCID:25885 Length:706 Species:Homo sapiens


Alignment Length:177 Identity:58/177 - (32%)
Similarity:87/177 - (49%) Gaps:9/177 - (5%)


- Green bases have known domain annotations that are detailed below.


  Fly   185 DRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKT 249
            ::|.|      |..|||.::....|..| ...|:.|..:.|..||.:.|...||.:|..:|.|:.
Human   539 EKPYK------CNECGKAFSVHSSLTIH-QTIHTGQKPYKCNDCGKVFRHNSYLAIHQRIHTGEK 596

  Fly   250 EKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICN 314
            ..:|..|.|:||...|...|..:|..:|.|:|.:||..|:|::.|.|||..|..|: |..|:.|.
Human   597 PYKCNECGKAFSVHSNLATHQVIHTGEKPYKCNECGKVFTQNSHLANHRRIHTGEK-PYRCNECG 660

  Fly   315 VSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEG 361
            .:|..|.|...|..:|..::| :.|:.|.|.||:...|..|.:.|.|
Human   661 KAFSVRSTLTTHMAVHTGDKP-YKCNQCGKVFTQNSNLAKHRRIHSG 706

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-deltaNP_524581.1 COG5048 <205..360 CDD:227381 50/154 (32%)
C2H2 Zn finger 225..245 CDD:275368 7/19 (37%)
C2H2 Zn finger 253..273 CDD:275368 7/19 (37%)
C2H2 Zn finger 281..301 CDD:275368 9/19 (47%)
C2H2 Zn finger 310..327 CDD:275370 5/16 (31%)
zf-C2H2 337..359 CDD:278523 7/21 (33%)
C2H2 Zn finger 339..359 CDD:275368 7/19 (37%)
ZNF665NP_001340387.1 KRAB 37..76 CDD:307490
COG5048 192..580 CDD:227381 13/47 (28%)
C2H2 Zn finger 208..228 CDD:275368
C2H2 Zn finger 236..256 CDD:275368
C2H2 Zn finger 264..284 CDD:275368
C2H2 Zn finger 292..312 CDD:275368
C2H2 Zn finger 320..340 CDD:275368
C2H2 Zn finger 348..368 CDD:275368
C2H2 Zn finger 376..396 CDD:275368
C2H2 Zn finger 404..424 CDD:275368
C2H2 Zn finger 432..452 CDD:275368
C2H2 Zn finger 460..480 CDD:275368
C2H2 Zn finger 488..508 CDD:275368
C2H2 Zn finger 516..536 CDD:275368
C2H2 Zn finger 544..564 CDD:275368 6/20 (30%)
C2H2 Zn finger 572..592 CDD:275368 7/19 (37%)
zf-H2C2_2 584..608 CDD:316026 8/23 (35%)
C2H2 Zn finger 600..620 CDD:275368 7/19 (37%)
zf-H2C2_2 612..637 CDD:316026 9/24 (38%)
C2H2 Zn finger 628..648 CDD:275368 9/19 (47%)
zf-H2C2_2 640..664 CDD:316026 9/24 (38%)
C2H2 Zn finger 656..676 CDD:275368 6/19 (32%)
zf-H2C2_2 669..693 CDD:316026 7/24 (29%)
C2H2 Zn finger 684..704 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165142347
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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