DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-delta and ZNF200

DIOPT Version :9

Sequence 1:NP_524581.1 Gene:Sry-delta / 43572 FlyBaseID:FBgn0003512 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_003445.2 Gene:ZNF200 / 7752 HGNCID:12993 Length:395 Species:Homo sapiens


Alignment Length:351 Identity:84/351 - (23%)
Similarity:147/351 - (41%) Gaps:48/351 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    31 PSSQ-KTVSLVLTHLANCIQTQLDLKPGARLCPRCFQELSDYDTIMVNLMTTQKRLTTQLKGALK 94
            ||.: |...:::..:::.:|.::..:|..:|.|:..|:  :.:|:.:.|....:.|      .:.
Human    62 PSQKVKETLVIMKDVSSSLQNRVHPRPLVKLLPKGVQK--EQETVSLYLKANPEEL------VVF 118

  Fly    95 SEFEVPESGED-ILVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEE-EEDD 157
            .:..|....|: :.::..:...|:.|.|:......|......:.|..|.|  ||.|:.|: .|..
Human   119 EDLNVFHCQEECVSLDPTQQLTSEKEDDSSVGEMMLLAVNGSNPEGEDPE--REPVENEDYREKS 181

  Fly   158 DDDDEFICEDVDVGDSEALYGKSSDGEDR-------PTKKRVKQECTTCGKVYNS--WYQLQKHI 213
            .||||.        ||..:..:..|.:::       |.|::::....|   :.|.  ..:|.|::
Human   182 SDDDEM--------DSSLVSQQPPDNQEKERLNTSIPQKRKMRNLLVT---IENDTPLEELSKYV 235

  Fly   214 -------SEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMR 271
                   :.....:..:.||:||....:..||..|...|.|:....|.:|.|||:...|..:|.|
Human   236 DISIIALTRNRRTRRWYTCPLCGKQFNESSYLISHQRTHTGEKPYDCNHCGKSFNHKTNLNKHER 300

  Fly   272 MHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEA---EENPIICSICNVSFKSRKTFNHHTLIHKEN 333
            :|..:|.|.|.:||..|.|:    :||.|||.   .|....|..|..:|...:.|..|...|:..
Human   301 IHTGEKPYSCSQCGKNFRQN----SHRSRHEGIHIREKIFKCPECGKTFPKNEEFVLHLQSHEAE 361

  Fly   334 RPRHYCSVCPKSFTERYTLKMHMKTH 359
            || :.|..|.:.|........|.|||
Human   362 RP-YGCKKCGRRFGRLSNCTRHEKTH 386

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-deltaNP_524581.1 COG5048 <205..360 CDD:227381 48/167 (29%)
C2H2 Zn finger 225..245 CDD:275368 7/19 (37%)
C2H2 Zn finger 253..273 CDD:275368 8/19 (42%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
C2H2 Zn finger 310..327 CDD:275370 4/16 (25%)
zf-C2H2 337..359 CDD:278523 5/21 (24%)
C2H2 Zn finger 339..359 CDD:275368 5/19 (26%)
ZNF200NP_003445.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 157..208 15/60 (25%)
COG5048 254..>395 CDD:227381 46/138 (33%)
C2H2 Zn finger 254..274 CDD:275368 7/19 (37%)
zf-H2C2_2 266..291 CDD:316026 10/24 (42%)
C2H2 Zn finger 282..302 CDD:275368 8/19 (42%)
C2H2 Zn finger 310..330 CDD:275368 10/23 (43%)
C2H2 Zn finger 338..358 CDD:275368 5/19 (26%)
C2H2 Zn finger 366..386 CDD:275368 5/19 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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