DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and zgc:136308

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001038712.1	Gene:	zgc:136308 / 692274	ZFINID:	ZDB-GENE-060512-206	Length:	320	Species:	Danio rerio

Alignment Length:	277	Identity:	73/277 - (26%)
Similarity:	112/277 - (40%)	Gaps:	53/277 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   179 KSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMN 243
            :.:|...|..|:||  .||.|||...:...|.||:.....|:| ..|..||....:::.|..||.
Zfish    12 EKTDSLKRKDKERV--TCTQCGKSLANKRSLGKHMRIHTGKKP-CTCTQCGKSLANKQSLGCHMR 73

  Fly   244 LHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPI 308
            :|..:....|..|.|||....|.:.||.:|...|.::|::||..|.:.:.|.:| ||...:|.|.
Zfish    74 VHTREKPFTCSQCGKSFGHLSNLISHMLIHNGDKTHKCDQCGKTFLRGSDLKSH-LRVHTKERPY 137

  Fly   309 ICSICNVSFK----------------------SRKTF------NHHTLIHKENRPRHYCSVCPKS 345
            .||:|..||:                      .:|||      ..|..||...:| :.||:|.|.
Zfish   138 PCSVCEKSFRHQVSLRNHQKTHTGVGEYRCLECKKTFITAENLKIHERIHTGEKP-YICSLCNKR 201

  Fly   346 FTERYTLKMHMKTHEGDVVYGV----REEAPADEQQVVEELHVDVDESEAAVTVIMSDNDENSGF 406
            |::...:|.|.:.|.|:..|..    :..:.....:..|.:|                ..|....
Zfish   202 FSQFAQMKSHERVHTGEKPYKCSHCDKRVSDLGNLRKHERIH----------------TGEKPYM 250

  Fly   407 CLICNTNFENKKELEHH 423
            |..|:|.|.:...|:.|
Zfish   251 CSHCDTRFSDLGTLKRH 267

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	51/182 (28%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	8/44 (18%)
		zf-C2H2	337..359	CDD:278523	7/21 (33%)
		C2H2 Zn finger	339..359	CDD:275368	7/19 (37%)
zgc:136308	NP_001038712.1	C2H2 Zn finger	27..47	CDD:275368	8/19 (42%)
		C2H2 Zn finger	55..75	CDD:275368	6/19 (32%)
		COG5048	<60..307	CDD:227381	55/226 (24%)
		C2H2 Zn finger	83..103	CDD:275368	8/19 (42%)
		C2H2 Zn finger	111..131	CDD:275368	8/20 (40%)
		zf-H2C2_2	123..148	CDD:290200	11/25 (44%)
		C2H2 Zn finger	139..159	CDD:275368	5/19 (26%)
		C2H2 Zn finger	167..187	CDD:275368	4/19 (21%)
		C2H2 Zn finger	195..215	CDD:275368	7/19 (37%)
		C2H2 Zn finger	223..243	CDD:275368	1/19 (5%)
		zf-H2C2_2	235..259	CDD:290200	6/39 (15%)
		C2H2 Zn finger	251..271	CDD:275368	6/17 (35%)
		zf-H2C2_2	264..288	CDD:290200	2/4 (50%)
		C2H2 Zn finger	279..299	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910