DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and zgc:113294

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001013567.1	Gene:	zgc:113294 / 541422	ZFINID:	ZDB-GENE-050320-124	Length:	332	Species:	Danio rerio

Alignment Length:	333	Identity:	89/333 - (26%)
Similarity:	145/333 - (43%)	Gaps:	36/333 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 EFEVPESGEDILVEEV-EIPQSDVETDADAEADALFVELVKDQEESDTEI---KREFVDEEEEED 156
            || :.|..|||.:||. .:...::|.         |:...:|.||...::   |.|..|:.|.|:
Zfish     2 EF-IKEESEDIKIEETFPVKHEEIEE---------FIIKYEDPEEQTEDLIPPKEEGQDQNEMEE 56

  Fly   157 DDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQP 221
            :|..:|: |:.....|||    :::...:...:|.....|..||:.:.....|.:|::..:.::|
Zfish    57 NDQYEEY-CDFTPEEDSE----QTNASSEETARKAKSNTCHQCGRSFTRKQYLIEHMTIHNGEKP 116

  Fly   222 NHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGL 286
             :.|..||.....::.|::||..|..:....|..|.|||:|..|..:||.:|..:|.|.||.||.
Zfish   117 -YTCQQCGKSFTWKQNLKIHMRTHTDEKPYTCHQCGKSFARNQNLSKHMGVHTGEKPYTCECCGK 180

  Fly   287 RFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYT 351
            .|::...|..| :|....|.|..|..|..:|..::....|..||...: .|.|:.|.||||.:..
Zfish   181 CFTRQQNLTGH-MRVHTGEKPYTCQHCGQNFTWKQNLTGHMSIHTGGK-AHACNQCGKSFTRKQN 243

  Fly   352 LKMHMKTHEGDVVYGVREEAPA-DEQQVVEELHVDVDESEAAVTVIMSDNDENSGFCLICNTNFE 415
            |..|||.|.....:...:...: ..:|::.| |:.....|...|            |..|..:|.
Zfish   244 LVDHMKIHTEGKAHTCHQCGKSFTRKQILTE-HMRTHTGEKPYT------------CQQCGKSFA 295

  Fly   416 NKKELEHH 423
            .|..|:.|
Zfish   296 TKAYLKRH 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	49/154 (32%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	3/16 (19%)
		zf-C2H2	337..359	CDD:278523	11/21 (52%)
		C2H2 Zn finger	339..359	CDD:275368	10/19 (53%)
zgc:113294	NP_001013567.1	COG5048	<71..207	CDD:227381	40/141 (28%)
		C2H2 Zn finger	91..111	CDD:275368	5/19 (26%)
		zf-H2C2_2	103..127	CDD:290200	6/24 (25%)
		C2H2 Zn finger	119..139	CDD:275368	6/19 (32%)
		zf-H2C2_2	131..156	CDD:290200	9/24 (38%)
		C2H2 Zn finger	147..167	CDD:275368	9/19 (47%)
		zf-H2C2_2	159..184	CDD:290200	11/24 (46%)
		C2H2 Zn finger	175..195	CDD:275368	8/20 (40%)
		zf-H2C2_2	187..211	CDD:290200	7/24 (29%)
		C2H2 Zn finger	203..223	CDD:275368	4/19 (21%)
		C2H2 Zn finger	231..251	CDD:275368	10/19 (53%)
		COG5048	259..>318	CDD:227381	11/58 (19%)
		C2H2 Zn finger	259..279	CDD:275368	3/20 (15%)
		zf-H2C2_2	272..296	CDD:290200	7/36 (19%)
		C2H2 Zn finger	287..307	CDD:275368	6/17 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910