DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and im:7141269

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_002661922.1	Gene:	im:7141269 / 492560	ZFINID:	ZDB-GENE-041111-134	Length:	368	Species:	Danio rerio

Alignment Length:	367	Identity:	98/367 - (26%)
Similarity:	155/367 - (42%)	Gaps:	72/367 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 LKSEFEVPESGEDI-LVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEED 156
            :|.|| :.|..||: ::|.|.|...|.|..||         ||:.:||     .:|.::.||:..
Zfish     1 MKMEF-IKEESEDVKIIEMVTIKYEDPEEQAD---------LVEPKEE-----PQELIEMEEKPQ 50

  Fly   157 DDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQE------CTTCGKVYNSWYQLQKHISE 215
                    ||...|..:|..:.:::....|.:|...|.:      |..|||.:.....|:.|::.
Zfish    51 --------CETQHVSATEEPHTEATQTSTRTSKSPQKSKPSSLFICCQCGKSFTRKQSLEGHMNL 107

  Fly   216 EHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQ 280
            .:.::| :.|..||...|.:..|.:||.:|.|:....|:.|.||||.......|||.|..:|.|.
Zfish   108 HNGEKP-YSCQQCGKSFRQKPNLRVHMRVHTGEKPYTCKQCGKSFSLVQGFKIHMRSHTGEKPYV 171

  Fly   281 CEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIH--------------- 330
            |::||..|||.: .:|...|....|.|..|.:|...|..::..|.|.:||
Zfish   172 CQQCGKGFSQIS-SFNSHTRIHTREKPYSCQLCGKDFSIKQHLNDHMIIHSAEKAFECQQCGKTF 235

  Fly   331 --KENRPRHY----------CSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELH 383
              |.:..:|.          |.:|..|||:.|:||.||:.|.|:..|..::......|....::|
Zfish   236 FLKRHLKKHIRVHSGEKNFTCQLCGNSFTQMYSLKRHMRIHSGEKPYSCQQCGKRFTQNNSLDIH 300

  Fly   384 VDVDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQ 425
            |             ..:.|.|..|..|..:|..|.:|.:|::
Zfish   301 V-------------RTHTERSFTCQECGESFNLKSDLNNHVK 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	53/181 (29%)
		C2H2 Zn finger	225..245	CDD:275368	7/19 (37%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	4/16 (25%)
		zf-C2H2	337..359	CDD:278523	11/31 (35%)
		C2H2 Zn finger	339..359	CDD:275368	10/19 (53%)
im:7141269	XP_002661922.1	COG5048	69..>362	CDD:227381	74/276 (27%)
		C2H2 Zn finger	88..108	CDD:275368	6/19 (32%)
		C2H2 Zn finger	116..136	CDD:275368	7/19 (37%)
		C2H2 Zn finger	144..164	CDD:275368	9/19 (47%)
		C2H2 Zn finger	172..192	CDD:275368	8/20 (40%)
		C2H2 Zn finger	200..220	CDD:275368	5/19 (26%)
		C2H2 Zn finger	228..248	CDD:275368	2/19 (11%)
		C2H2 Zn finger	256..276	CDD:275368	10/19 (53%)
		C2H2 Zn finger	284..304	CDD:275368	3/32 (9%)
		C2H2 Zn finger	311..331	CDD:275368	6/19 (32%)
		C2H2 Zn finger	339..359	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910