DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and CG30431

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	351	Identity:	70/351 - (19%)
Similarity:	127/351 - (36%)	Gaps:	64/351 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 SLVLTHLANCIQTQLD------------LKPGARLCPRCFQELSDYDTI-MVNLMTTQKRLTTQL 89
            :|.|..:..|::.::.            .||.|.:.|  ..|..|:::: ..:...::..:.:..
  Fly    97 ALALDDVLECLEREVGSLEGPMSVPLQASKPVAHVAP--LMETVDFESLDFQDSSHSEHDIPSYW 159

  Fly    90 K-----GALKSEFEVPESGEDILVEEVEIPQSDVETDADAEADALFVELVKDQEESDTEIKREFV 149
            :     |:|.:....||:.|...||....|:|..|...||            .|:......|...
  Fly   160 ESSVDSGSLNTPHHQPETAELFAVEPPTPPESSEEPAPDA------------AEKPKMRRARPRQ 212

  Fly   150 DEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHIS 214
            |..:.::                      :.:.|...|   |....|..|.|.:...:||:.|::
  Fly   213 DNVKPKE----------------------RKASGAVHP---RSLHPCPECEKKFTRNFQLKLHMT 252

  Fly   215 EEHSK-QPNHICPICGVIRRDEEYLELHM-NLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKK 277
            ..|.. :..:.|..|.........|..|: ::|..:....|::|.:.|......|.|:|.|..:.
  Fly   253 AVHGMGEMRYQCEECRKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEA 317

  Fly   278 K---YQCEKCGLRFSQDNLLYNHRLRHEAE-ENPIICSICNVSFKSRKTFNHHTLIHKENRPRHY 338
            |   ::|::|...:...:.|..|...|... |.|..|..|:.:|.:|...|.|.|:|...:| ..
  Fly   318 KPRIFECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTGEKP-FA 381

  Fly   339 CSVCPKSFTERYTLKMHMKTHEGDVV 364
            |..|.|.:.....|..||.....|::
  Fly   382 CEYCDKCYQSVGNLNNHMVRLHADII 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	39/160 (24%)
		C2H2 Zn finger	225..245	CDD:275368	4/20 (20%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		C2H2 Zn finger	281..301	CDD:275368	4/19 (21%)
		C2H2 Zn finger	310..327	CDD:275370	5/16 (31%)
		zf-C2H2	337..359	CDD:278523	6/21 (29%)
		C2H2 Zn finger	339..359	CDD:275368	6/19 (32%)
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/20 (30%)
		C2H2 Zn finger	264..285	CDD:275368	4/20 (20%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		zf-C2H2_8	305..373	CDD:292531	18/67 (27%)
		C2H2 Zn finger	324..344	CDD:275368	4/19 (21%)
		C2H2 Zn finger	354..374	CDD:275368	7/19 (37%)
		zf-H2C2_2	366..389	CDD:290200	8/23 (35%)
		C2H2 Zn finger	382..403	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100