DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and CG1529

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001138223.2	Gene:	CG1529 / 33077	FlyBaseID:	FBgn0031144	Length:	512	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	104/436 - (23%)
Similarity:	159/436 - (36%)	Gaps:	134/436 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 ARLCPRCFQELSDYDTIMVN---LMTTQKRLTTQLKGALKSEFEVP------------------- 100
            ||||..|.:.|.|.||...:   :...||.|...:   ||.....|
  Fly     9 ARLCRICLRHLRDRDTHCPDPRLIAILQKLLDIDI---LKQPHGFPTEICNLCHNAVVYFDELRQ 70

  Fly   101 ---ESGE--------DILVEEV-------------EIPQSDVETDADAEADALFVELVKDQEESD 141
               ||.:        ||.|:.|             |..:.::|.:.:.:||...|:|.|.||:
  Fly    71 VARESSQKLIGWQPVDIAVDRVKEEPPDEGLKENHEENEHELEEEHEKQADGQQVDLSKKQED-- 133

  Fly   142 TEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQECTTCGK-VYNS 205
               :::.:|:.|:|:..|:.|...:.:..|..              :|:|....|..||| ||
  Fly   134 ---QKKILDDREDEEYPDEYENSQQQLSQGTG--------------SKRRAGLACDQCGKQVY-- 179

  Fly   206 WYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHM-NLHEGKTEK-QCRYCPKSFSRPVNTLR 268
                         |.|               |||.|: ::|:|.::. .||.|.|||:|......
  Fly   180 -------------KLP---------------YLEAHIRSVHQGYSKPFLCRSCDKSFTRYEQLRS 216

  Fly   269 HMR-MHWDKKKYQ-------CEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNH 325
            ||| .|...::.|       ||.|..::|..|.|..|..|| |:....:|..|.|:..:|.....
  Fly   217 HMRNAHPQLEQLQQELRDLICELCNRQYSTKNALGEHLKRH-AQRKEHVCEHCGVAKVTRTELLT 280

  Fly   326 HTLIHKENRPRHYCSVCPKSFTERYTLKMHMK-THEG---------DVVYGVREEAPADEQQVVE 380
            |...|.....|..|..||:.|..:..:..|:: .|||         :..:|...     .|...|
  Fly   281 HLRTHNPTWERFKCEQCPQLFRHKSAISRHVRVVHEGQRRFQCGHCEKKFGTHA-----SQVRHE 340

  Fly   381 ELHVD-VDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQ 425
            .||.: ....|||        :|....|:.|.....:::.||.||:
  Fly   341 RLHTESTGSGEAA--------EEWPFACIHCQKPCVSRQTLELHLR 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	42/165 (25%)
		C2H2 Zn finger	225..245	CDD:275368	4/20 (20%)
		C2H2 Zn finger	253..273	CDD:275368	10/20 (50%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	4/16 (25%)
		zf-C2H2	337..359	CDD:278523	5/22 (23%)
		C2H2 Zn finger	339..359	CDD:275368	5/20 (25%)
CG1529	NP_001138223.2	zf-AD	11..79	CDD:285071	15/70 (21%)
		C2H2 Zn finger	171..192	CDD:275368	12/50 (24%)
		zf-C2H2_2	201..>257	CDD:289522	19/55 (35%)
		C2H2 Zn finger	201..222	CDD:275368	10/20 (50%)
		C2H2 Zn finger	237..257	CDD:275368	7/19 (37%)
		C2H2 Zn finger	265..285	CDD:275368	5/19 (26%)
		zf-C2H2_8	268..349	CDD:292531	19/85 (22%)
		C2H2 Zn finger	294..315	CDD:275368	5/20 (25%)
		C2H2 Zn finger	323..343	CDD:275368	3/24 (13%)
		C2H2 Zn finger	360..380	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100