DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and CG43347

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001138185.2	Gene:	CG43347 / 31991	FlyBaseID:	FBgn0263072	Length:	2684	Species:	Drosophila melanogaster

Alignment Length:	430	Identity:	96/430 - (22%)
Similarity:	147/430 - (34%)	Gaps:	136/430 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEV-----------------------PESGEDILV 108
            :||:.:|         |.|.|..:.::.:|||:                       |..|:.:..
  Fly  1014 QLSELET---------KPLITFAEASVPAEFELHNVEPNVTGVFARTEVRAFTKLGPLIGQPVQT 1069

  Fly   109 EEVEIPQSDVE-----TDADAEADAL-------------FVELVKDQEESD---TEIKRE--FVD 150
            .||. ..||::     .:|.|:...|             ||......||.:   ..|.|:  ||.
  Fly  1070 GEVR-EGSDMKWIFEMCEAGADKSYLLCCDNPNASNWLRFVRPAPSYEERNVNLVSIDRQAYFVS 1133

  Fly   151 EEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRV-KQECTTCGKVYNSWYQLQKHIS 214
                          |.|:..| .|.||. |.|......||.. |..|..|...:......:.|.|
  Fly  1134 --------------CRDLRNG-MELLYW-SDDCNTMWRKKHTEKTNCGGCNLKFEHPLYYRTHCS 1182

  Fly   215 EEHSKQPN-----HICPICG--VIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRM 272
            ..|....:     :.|.:||  |:.:| ..::.....|:||...||::|.|.|.|    |.::.|
  Fly  1183 VFHDPSMSLTIRKYHCKVCGEPVLGKD-NIMKHAAEKHDGKGAYQCQFCSKFFLR----LNYLEM 1242

  Fly   273 HW--------DKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPII----CSICNVSFKSRKTFNH 325
            |.        ::.:..|:.||.:|.|...|..|..|..::...::    |.:|:....||.....
  Fly  1243 HRTYGCASNPNRSRPVCDFCGRKFCQPQKLKAHIKRMHSDMAEVLRDFQCKLCSKLLGSRAALQR 1307

  Fly   326 HTL-IHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELHVDVDES 389
            |:. :|..|.....|..|.|.|..|..||:||.||.     |||....|:.:
  Fly  1308 HSKEVHSRNSTVVSCPRCQKLFQNRSNLKIHMLTHS-----GVRPFKCAEPE------------- 1354

  Fly   390 EAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQFDHD 429
                                ||..|..|:.|:.|.:..|:
  Fly  1355 --------------------CNAAFTTKQCLQFHYKKVHN 1374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	45/174 (26%)
		C2H2 Zn finger	225..245	CDD:275368	5/21 (24%)
		C2H2 Zn finger	253..273	CDD:275368	6/19 (32%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	4/16 (25%)
		zf-C2H2	337..359	CDD:278523	9/21 (43%)
		C2H2 Zn finger	339..359	CDD:275368	9/19 (47%)
CG43347	NP_001138185.2	NR_DBD_like	1198..>1268	CDD:295381	21/74 (28%)
		C2H2 Zn finger	1198..1219	CDD:275368	5/21 (24%)
		C2H2 Zn finger	1227..1255	CDD:275368	8/31 (26%)
		C2H2 Zn finger	1259..1280	CDD:275368	8/20 (40%)
		C2H2 Zn finger	1292..1313	CDD:275368	5/20 (25%)
		C2H2 Zn finger	1322..1342	CDD:275368	9/19 (47%)
		zf-H2C2_2	1334..1361	CDD:290200	13/64 (20%)
		C2H2 Zn finger	1350..1373	CDD:275368	7/55 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100