DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and CG2129

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster

Alignment Length:	389	Identity:	80/389 - (20%)
Similarity:	147/389 - (37%)	Gaps:	120/389 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 DLKPGARLCPRCFQELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEVPESGEDILVEEVEIPQSD 117
            |.:||     |...:..|:.::      |.:.| .|:: |||.:::..:|.::         :..
  Fly   122 DERPG-----RSIIKWQDHQSL------TSESL-RQVR-ALKVDYKEEDSEQE---------ECG 164

  Fly   118 VETDADAEA--DALF-------VELVKDQEESDTEIKREFVDEEEEEDDDDDDEFICEDVDVGDS 173
            :|.|.|:|.  .|..       .::.:.::..:..|.|:..|....:.|.:|.::
  Fly   165 MELDLDSEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADY---------- 219

  Fly   174 EALYGKSSDGEDRPTKKRVKQ-ECTTCGKVYNSWYQLQKHISEEH-----------------SKQ 220
                   ...:|.|.|...:: :|..|||:|:..|.|::|:..:|                 ::.
  Fly   220 -------EPPKDAPVKSAAQEYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQL 277

  Fly   221 P------NHI--------CPICGVIRRDEEYLELHMNLHEGKTEKQCRY--CPKSFSRPVNTLRH 269
            |      .|:        |.:||...:....|:.|...|..:....|.:  |.|.|.    |:||
  Fly   278 PRLRLLDEHMVQAHGGAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFF----TIRH 338

  Fly   270 MR----MHWDKKKYQCEKCGL----------------------------RFSQDNLLYNHRLRHE 302
            ||    :|.::|.:.||.||.                            ||...:.|..|...|
  Fly   339 MRNHGKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMH- 402

  Fly   303 AEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYG 366
            :.|.|.:||:|..:|..:|...||..:|.:.: :..|.:|..::.:...|..||:.|..|.:.|
  Fly   403 STERPHVCSVCGATFSRQKGLYHHKFLHADTK-QFVCKLCGNAYAQAAGLAGHMRKHRNDELNG 465

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	47/219 (21%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		C2H2 Zn finger	253..273	CDD:275368	9/25 (36%)
		C2H2 Zn finger	281..301	CDD:275368	8/47 (17%)
		C2H2 Zn finger	310..327	CDD:275370	6/16 (38%)
		zf-C2H2	337..359	CDD:278523	5/21 (24%)
		C2H2 Zn finger	339..359	CDD:275368	5/19 (26%)
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	5/19 (26%)
		zf-C2H2_8	323..411	CDD:292531	22/92 (24%)
		C2H2 Zn finger	327..346	CDD:275368	8/22 (36%)
		C2H2 Zn finger	354..374	CDD:275368	4/19 (21%)
		zf-H2C2_2	367..389	CDD:290200	0/21 (0%)
		C2H2 Zn finger	382..402	CDD:275368	4/19 (21%)
		zf-H2C2_2	395..419	CDD:290200	9/24 (38%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440002
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	59	1.000	Inparanoid score	I2552
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.980