DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and CG2120

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	354	Identity:	80/354 - (22%)
Similarity:	125/354 - (35%)	Gaps:	118/354 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 ELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEVPESGEDILVE-EVEIPQSDVETDADAEADALF 130
            :|.:||..:.:|     :|..||:..         |||.:.:| |:..|.|:.:          .
  Fly    19 DLGNYDVCLEDL-----QLFAQLEDL---------SGERLPMEMELLNPGSEYD----------L 59

  Fly   131 VELVKD--QEESDTEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVK 193
            :|||..  |:.:.||.|               ...:|:.                :..||.||.:
  Fly    60 LELVNGALQQRNTTEHK---------------PTDMCKP----------------KRTPTTKRHR 93

  Fly   194 -----QECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQC 253
                 ..|..|.:.::..|.|:.| ...|:.:..|:|..||...|....|.:|...|..:...:|
  Fly    94 TTGKDHTCDICDRRFSEAYNLRIH-KMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKC 157

  Fly   254 RYCPKSFSRPVNTLR-HMRMHWDKKKYQC--EKCGLRFSQDNLLYNH-RLRHEAEENP------- 307
            ..|.|.| |..|.|. |.|:|..:|.|.|  ..|.|.|...:....| :|||.|:.:|
  Fly   158 DICGKGF-RYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLA 221

  Fly   308 -----------IICSICN--------VSFKSRKTFN----------------------HHTLIHK 331
                       ..|.:|:        :|...::.:|                      ||.:.|.
  Fly   222 EQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHT 286

  Fly   332 ENRPRHYCSVCPKSFTERYTLKMHMKTHE 360
            :.|| ..|.:||..|..:...|.|:|.||
  Fly   287 QQRP-FACPLCPARFLRKSNHKQHLKVHE 314

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	50/206 (24%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	9/20 (45%)
		C2H2 Zn finger	281..301	CDD:275368	6/22 (27%)
		C2H2 Zn finger	310..327	CDD:275370	5/46 (11%)
		zf-C2H2	337..359	CDD:278523	7/21 (33%)
		C2H2 Zn finger	339..359	CDD:275368	7/19 (37%)
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	5/20 (25%)
		zf-H2C2_2	113..138	CDD:290200	7/25 (28%)
		C2H2 Zn finger	129..149	CDD:275368	6/19 (32%)
		zf-H2C2_2	142..166	CDD:290200	7/24 (29%)
		COG5048	151..>264	CDD:227381	26/113 (23%)
		C2H2 Zn finger	157..177	CDD:275368	9/20 (45%)
		C2H2 Zn finger	185..206	CDD:275368	5/20 (25%)
		C2H2 Zn finger	235..255	CDD:275368	3/19 (16%)
		C2H2 Zn finger	263..285	CDD:275368	2/21 (10%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100