DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sry-delta and CG11398

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001259122.2	Gene:	CG11398 / 31070	FlyBaseID:	FBgn0040366	Length:	329	Species:	Drosophila melanogaster

Alignment Length:	363	Identity:	80/363 - (22%)
Similarity:	124/363 - (34%)	Gaps:	108/363 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   123 DAEADALFVELVKDQEES--DTEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALY-GKSSDGE 184
            :||..||.....:|:|.|  ..|::.|.::|..:........|:|.     ...||: .:.....
  Fly     8 EAEILALLPHTYEDEELSLNTEELQFEELNERSQHQQGGSPSFVCR-----RCPALFLTREELAA 67

  Fly   185 DRPTKK--------RVKQECTTCGKVYNSWYQL----------------------------QKHI 213
            .|||.:        ..:..|..||:|:.....|                            :.|:
  Fly    68 HRPTHRYQGGQQTPASEHACDACGRVFQKHNALVDHMNAHNDVRNYPCPECPARFVQRSNRECHL 132

  Fly   214 SEEHSKQPNHICPICGVIRRDEEYLELHMN---LHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWD 275
            ...|.|...|.||..|..:|.::..|...:   :|:.:....|..|...||.|||..:|:..|..
  Fly   133 KNVHRKVYLHSCPEPGCKKRFQQRRECDQHVKTVHQNERNLVCDTCSARFSHPVNYRKHLASHGS 197

  Fly   276 KKKYQCEKCGLRF----SQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLI---HKE- 332
            .|.|.|..||..|    ::|..|:.|.:.     ...|||:|...:..|.....|.|.   |.:
  Fly   198 AKSYGCPICGKLFGRPENRDVHLFVHSIC-----KAYICSVCGADYMRRNQLIRHGLASGHHNDP 257

  Fly   333 ---NRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELH----VDVDESE 390
               .:|:...::..|:.::|..:                     ||.| .|||.    ||..:|.
  Fly   258 IVRQKPQFSPALAAKNRSQRSAI---------------------DESQ-DEELQWLKGVDALDSA 300

  Fly   391 AAVTVIMSDNDENSGFCLICNT--------NFENKKEL 420
            ..:        |||.|   .||        ..||:.||
  Fly   301 GYL--------ENSQF---SNTGKMTAIFAEDENESEL 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	40/196 (20%)
		C2H2 Zn finger	225..245	CDD:275368	5/22 (23%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		C2H2 Zn finger	281..301	CDD:275368	7/23 (30%)
		C2H2 Zn finger	310..327	CDD:275370	4/16 (25%)
		zf-C2H2	337..359	CDD:278523	2/21 (10%)
		C2H2 Zn finger	339..359	CDD:275368	2/19 (11%)
CG11398	NP_001259122.2	C2H2 Zn finger	52..72	CDD:275368	5/24 (21%)
		C2H2 Zn finger	87..107	CDD:275368	5/19 (26%)
		C2H2 Zn finger	115..136	CDD:275368	1/20 (5%)
		C2H2 Zn finger	144..165	CDD:275368	5/20 (25%)
		C2H2 Zn finger	175..195	CDD:275368	8/19 (42%)
		C2H2 Zn finger	203..223	CDD:275368	6/19 (32%)
		C2H2 Zn finger	231..247	CDD:275368	4/15 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100