DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and let-391

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_491744.3	Gene:	let-391 / 182953	WormBaseID:	WBGene00006492	Length:	453	Species:	Caenorhabditis elegans

Alignment Length:	184	Identity:	45/184 - (24%)
Similarity:	75/184 - (40%)	Gaps:	18/184 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   249 TEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICS-I 312
            |..||..|......|.....|:|.|..:|.::|.:|||..|:.:.|..|..|....|.|..|: .
Worm   266 TLAQCNICGLMLKHPSKIADHIRTHTGEKPFECGECGLSLSKASSLKVHIRRMHTGERPFECTWR 330

  Fly   313 CNVSFKSRKTFNHHTLIHKENRPRHYCSV--CPKSFTERYTLKMHMKTHEGDVVYGVREEAPADE 375
            |.:||.:......|.:.......|:.|.|  |...|..|..|..|.|....::.
Worm   331 CGLSFVTDSVRKEHEMTVHTGIKRYTCVVKGCNAVFARRVYLMRHRKNAHPELF----------- 384

  Fly   376 QQVVEELHVDVDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQFDHD 429
            ..:.:.:.|:.:||:.:|.|...|:::|:...::.... ::.|.|.|   |:.|
Worm   385 TPIFDHVQVNHEESQDSVIVYEDDHEQNNQIIMLTGDG-DDVKILAH---FEDD 434

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	33/113 (29%)
		C2H2 Zn finger	225..245	CDD:275368
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		C2H2 Zn finger	281..301	CDD:275368	7/19 (37%)
		C2H2 Zn finger	310..327	CDD:275370	4/17 (24%)
		zf-C2H2	337..359	CDD:278523	8/23 (35%)
		C2H2 Zn finger	339..359	CDD:275368	8/21 (38%)
let-391	NP_491744.3	C2H2 Zn finger	59..79	CDD:275368
		zf-H2C2_2	73..96	CDD:290200
		C2H2 Zn finger	87..108	CDD:275368
		C2H2 Zn finger	116..137	CDD:275368
		C2H2 Zn finger	270..290	CDD:275368	5/19 (26%)
		zf-H2C2_2	286..304	CDD:290200	7/17 (41%)
		C2H2 Zn finger	298..319	CDD:275368	8/20 (40%)
		C2H2 Zn finger	327..347	CDD:275368	5/19 (26%)
		C2H2 Zn finger	357..377	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100