DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and LOC101882575

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_021326494.1	Gene:	LOC101882575 / 101882575	-ID:	-	Length:	346	Species:	Danio rerio

Alignment Length:	366	Identity:	91/366 - (24%)
Similarity:	145/366 - (39%)	Gaps:	64/366 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 QELSDYDTIMVNLMTTQKRLTTQLKGALKSEFEVPESGEDILVEEVEIPQSDVETDADAEADALF 130
            |.||.:..:|:..:.::   .|:.:..:|..| :.|..|||.:||....:.: ||:     :|..
Zfish    14 QRLSHFPLLMMLFILSK---PTEQQIIIKMAF-IKEESEDIKIEETFTVKHE-ETE-----EAFR 68

  Fly   131 VELVKDQEESD-TEIKREFVDEEEEEDDDDDDEFICEDVDVGDSEALYGKSSDGEDRPTKKRVKQ 194
            |:....:|::| ..:|:|..|:.|.|:.....:.        ..|....|:|  .:|..:|....
Zfish    69 VKHEDPEEQTDLMPLKKESQDQNEIEEKHQHKKI--------PEEREQRKTS--SERTAQKTESN 123

  Fly   195 ECTTCGKVYNSWYQLQKHISEEHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKS 259
            .|..|||.:.......||:......:| :.|..||.....::.|.:||.:|.|:....|.||.||
Zfish   124 TCHECGKSFTRKQSFTKHMRVHTGAKP-YTCSQCGKSFTWKQNLTMHMMIHTGEKPHACLYCEKS 187

  Fly   260 FSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFN 324
            |....:...||.:|...|.:.|.:||..|:....|..| :|....|.|..|..|..||...:::.
Zfish   188 FISKQSLTNHMEVHTGGKPHTCHQCGKSFTWKQYLTQH-MRIHTGEKPHSCQQCGKSFTWTQSYR 251

  Fly   325 HHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELHVDVDES 389
            :|...|.:.|| :.|..|.|||..:..||.||..|.|:.:|.
Zfish   252 NHMRNHTKERP-YVCQQCGKSFIWKQNLKNHMNAHTGEKLYS----------------------- 292

  Fly   390 EAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQFDHDV 430
                             |..|..:|..|:.|..||:....|
Zfish   293 -----------------CQYCGKSFTWKQSLTDHLKIHSGV 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	47/154 (31%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	8/19 (42%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..327	CDD:275370	4/16 (25%)
		zf-C2H2	337..359	CDD:278523	9/21 (43%)
		C2H2 Zn finger	339..359	CDD:275368	9/19 (47%)
LOC101882575	XP_021326494.1	COG5048	<74..272	CDD:227381	57/210 (27%)
		C2H2 Zn finger	125..145	CDD:275368	6/19 (32%)
		C2H2 Zn finger	153..173	CDD:275368	6/19 (32%)
		C2H2 Zn finger	181..201	CDD:275368	8/19 (42%)
		C2H2 Zn finger	209..229	CDD:275368	7/20 (35%)
		C2H2 Zn finger	237..257	CDD:275368	5/19 (26%)
		C2H2 Zn finger	265..285	CDD:275368	9/19 (47%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		C2H2 Zn finger	321..341	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910