DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sry-delta and znf1053

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	XP_017211055.1	Gene:	znf1053 / 100150608	ZFINID:	ZDB-GENE-121214-1	Length:	448	Species:	Danio rerio

Alignment Length:	387	Identity:	92/387 - (23%)
Similarity:	146/387 - (37%)	Gaps:	96/387 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    99 VPESGEDILVEEV-EIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDDDDDDE 162
            :.|..||:.:||. .:.|.|:                  ||::|    |..:.||..|.::.|::
Zfish     4 IKEESEDVKIEETFTVKQEDL------------------QEQTD----RMVLKEETHEQNEIDEK 46

  Fly   163 FICE---DVDVGDSEALYGK-SSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISEEHSKQPNH 223
            .:.|   ::...:...|..| ||.|..|.:|......|..|.|.:|....|..|: ..|:.:..:
Zfish    47 LLFEKPQEITTDEKPTLTKKTSSHGRPRKSKSGCNFSCKQCRKSFNQKSNLHVHL-RVHTWEKPY 110

  Fly   224 ICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRF 288
            .|..||......:..::||.:|.|:::..|:.|.|||....|...|||:|..:|.:.|::||..|
Zfish   111 TCKQCGKSFSQIQGFKVHMRIHTGESKFTCQECGKSFYHAGNFAAHMRIHTGEKPFSCKQCGKSF 175

  Fly   289 SQDNLLYNHRLRHEAE---------------------------ENPIICSICNVSFKSRKTFNHH 326
            ||...|..|...|..|                           |.|..|..|..||..:::|..|
Zfish   176 SQKPNLDIHMRIHTGEKPFSCKQCGKSFSQKSHLDIHMRVHTGEKPYTCEQCGQSFSQKQSFKSH 240

  Fly   327 TLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVRE--------------------EA 371
            ..||...|| :.|..|.|:|.....|..||:.|.|:..:..::                    |.
Zfish   241 MRIHTGERP-YTCQQCGKNFRHARNLAAHMRIHTGEKPFSCKQCGKSFSKKANLIAHMRVHTREK 304

  Fly   372 PADEQQVVEEL--------HVDVDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQ 425
            |...:|..:.|        |:.:...|...|            |..|..:|.:...|:||::
Zfish   305 PYTCEQCGKSLGKKQDLYIHMRIHTGEKPYT------------CTECGKSFPHITTLKHHVR 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	50/181 (28%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		C2H2 Zn finger	281..301	CDD:275368	8/19 (42%)
		C2H2 Zn finger	310..327	CDD:275370	5/16 (31%)
		zf-C2H2	337..359	CDD:278523	7/21 (33%)
		C2H2 Zn finger	339..359	CDD:275368	7/19 (37%)
znf1053	XP_017211055.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910