DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-delta and zgc:174646

DIOPT Version :9

Sequence 1:NP_524581.1 Gene:Sry-delta / 43572 FlyBaseID:FBgn0003512 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_001116087.1 Gene:zgc:174646 / 100142637 ZFINID:ZDB-GENE-080305-6 Length:408 Species:Danio rerio


Alignment Length:356 Identity:93/356 - (26%)
Similarity:140/356 - (39%) Gaps:50/356 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    99 VPESGEDILVEEV-EIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDDD---- 158
            :.|..||:.:||. .:.|.|::...|         |:||.|||..|..|..::.:...:..    
Zfish     4 IKEENEDVKIEETFTVKQEDLQEQTD---------LIKDYEESKEEEHRVKIEGKTHLETGGILK 59

  Fly   159 --DDDEFICEDVDVGDSEA------LYGKSSDGEDRPTKKRVKQECTTCGKVYNSWYQLQKHISE 215
              |...|.|  ...|.|.|      ::.|...||...|       ||.|||.::....|.:|:..
Zfish    60 TRDKSCFTC--TQCGKSLANKSKLKIHMKIHTGEKPFT-------CTQCGKSFSHSANLNQHMMI 115

  Fly   216 EHSKQPNHICPICGVIRRDEEYLELHMNLHEGKTEKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQ 280
            ....:| ..|..||........|..||.:|.|:....|..|.|||::|.|...|||:|..:|.:.
Zfish   116 HTGGKP-FTCHQCGKSFSKPSTLYRHMRIHTGEQPFTCTQCGKSFNQPSNLNLHMRIHTGEKPFT 179

  Fly   281 CEKCGLRFSQDNLLYNHRLRHEAEENPIICSICNVSFKSRKTFNHHTLIHKENRPRHYCSVCPKS 345
            |.:||..|...:.|..|.:.|..|: |..|:.|..||....|.|.|..||...:| ..|:.|.||
Zfish   180 CTQCGKNFIHSSHLNEHMMIHTGEK-PFTCTQCGRSFSLSSTLNRHMRIHTGEKP-FTCTQCGKS 242

  Fly   346 FTERYTLKMHMKTHEGDVVYGVREEAPADEQQVVEELHVDVDESEAAVTV--------------- 395
            |::..:|..||:.|.|:..:...:...:.........|:.:...|.....               
Zfish   243 FSQSASLNRHMRIHTGESPFTCTQCGKSFSLSSYLNKHMRIHTGEKPFICTRCGKSFRHSSHLNQ 307

  Fly   396 -IMSDNDENSGFCLICNTNFENKKELEHHLQ 425
             :|..|.|....|..|..:|.:...|..|::
Zfish   308 HMMIHNREKPFTCTCCGKSFRHSSSLNQHMR 338

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-deltaNP_524581.1 COG5048 <205..360 CDD:227381 50/154 (32%)
C2H2 Zn finger 225..245 CDD:275368 6/19 (32%)
C2H2 Zn finger 253..273 CDD:275368 10/19 (53%)
C2H2 Zn finger 281..301 CDD:275368 6/19 (32%)
C2H2 Zn finger 310..327 CDD:275370 6/16 (38%)
zf-C2H2 337..359 CDD:278523 8/21 (38%)
C2H2 Zn finger 339..359 CDD:275368 8/19 (42%)
zgc:174646NP_001116087.1 C2H2 Zn finger 68..88 CDD:275368 5/21 (24%)
zf-H2C2_2 81..105 CDD:290200 9/30 (30%)
C2H2 Zn finger 96..116 CDD:275368 7/19 (37%)
zf-H2C2_2 108..132 CDD:290200 6/24 (25%)
C2H2 Zn finger 124..144 CDD:275368 6/19 (32%)
COG5048 <129..391 CDD:227381 56/212 (26%)
zf-H2C2_2 137..161 CDD:290200 10/23 (43%)
C2H2 Zn finger 152..172 CDD:275368 10/19 (53%)
zf-H2C2_2 164..187 CDD:290200 9/22 (41%)
C2H2 Zn finger 180..200 CDD:275368 6/19 (32%)
zf-H2C2_2 192..216 CDD:290200 8/24 (33%)
C2H2 Zn finger 208..228 CDD:275368 7/19 (37%)
zf-H2C2_2 221..245 CDD:290200 10/24 (42%)
C2H2 Zn finger 236..256 CDD:275368 8/19 (42%)
zf-H2C2_2 248..272 CDD:290200 5/23 (22%)
C2H2 Zn finger 264..284 CDD:275368 1/19 (5%)
zf-H2C2_2 276..301 CDD:290200 2/24 (8%)
C2H2 Zn finger 292..312 CDD:275368 1/19 (5%)
C2H2 Zn finger 320..340 CDD:275368 5/19 (26%)
zf-H2C2_2 332..356 CDD:290200 2/7 (29%)
C2H2 Zn finger 348..368 CDD:275368
C2H2 Zn finger 375..395 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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