DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-delta and zgc:173714

DIOPT Version :9

Sequence 1:	NP_524581.1	Gene:	Sry-delta / 43572	FlyBaseID:	FBgn0003512	Length:	433	Species:	Drosophila melanogaster
Sequence 2:	NP_001103310.1	Gene:	zgc:173714 / 100126112	ZFINID:	ZDB-GENE-071004-90	Length:	359	Species:	Danio rerio

Alignment Length:	371	Identity:	88/371 - (23%)
Similarity:	144/371 - (38%)	Gaps:	79/371 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 EDILVEEV-EIPQSDVETDADAEADALFVELVKDQEESDTEIKREFVDEEEEEDDDDDDE----- 162
            ||:.:||. .:.|.|::...|       :.::|::.....||      ||:.:|...|::
Zfish     9 EDVKIEETFTVKQEDLQEQTD-------LMVLKEETHQWNEI------EEKHQDITTDEKPTLTK 60

  Fly   163 --FICEDVDVGDSEALY-GKSS----------DGEDRPTKKRVKQECTTCGKVYNSWYQ------ 208
              ..|.......|:..: ||.|          |...|..|.:....|..|||   |:|:
Zfish    61 MTSSCRRPRKSKSKCNFSGKQSRKSFSQKPKLDVHMRVHKGKKTCTCKQCGK---SFYKTSSLTM 122

  Fly   209 -LQKHISEE-----------------------HSKQPNHICPICGVIRRDEEYLELHMNLHEGKT 249
             ::.|..|:                       |:.:..:.|..||.....:|..:.||..|.|:.
Zfish   123 YMRIHTGEKPYTCKQCGKSFCNTTNLTMHMRIHTGEKPYTCGQCGKSFCQKENFKTHMRTHTGER 187

  Fly   250 EKQCRYCPKSFSRPVNTLRHMRMHWDKKKYQCEKCGLRFSQDNLLYNHRLRHEAEENPIICSICN 314
            ...|:.|.|||....|...|||:|..::.|.|::||..|.....|..|...|..|: |..|:.|.
Zfish   188 PYTCQQCGKSFRHAGNFTVHMRIHTGERSYTCQQCGKGFYHAGSLAVHMKVHTGEK-PYTCTECG 251

  Fly   315 VSFKSRKTFNHHTLIHKENRPRHYCSVCPKSFTERYTLKMHMKTHEGDVVYGVREEAPADEQQVV 379
            .||..:.:.|||...|...:| ..|:.|.||||.:.:|..|:..|.|.:|:            ..
Zfish   252 KSFPHKSSINHHMRTHTGEKP-FACAQCGKSFTTKSSLMNHLNGHTGTIVF------------TC 303

  Fly   380 EELHVDVDESEAAVTVIMSDNDENSGFCLICNTNFENKKELEHHLQ 425
            ::..:.:...:.....:.:.:.||...|..|...|.:|:.|..||:
Zfish   304 DQCGIKLTRKDYIRRHMKTHSRENRFRCSECGKGFTHKRSLSAHLK 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-delta	NP_524581.1	COG5048	<205..360	CDD:227381	50/184 (27%)
		C2H2 Zn finger	225..245	CDD:275368	6/19 (32%)
		C2H2 Zn finger	253..273	CDD:275368	9/19 (47%)
		C2H2 Zn finger	281..301	CDD:275368	6/19 (32%)
		C2H2 Zn finger	310..327	CDD:275370	6/16 (38%)
		zf-C2H2	337..359	CDD:278523	8/21 (38%)
		C2H2 Zn finger	339..359	CDD:275368	8/19 (42%)
zgc:173714	NP_001103310.1	COG5048	<41..336	CDD:227381	75/317 (24%)
		C2H2 Zn finger	107..127	CDD:275368	6/22 (27%)
		zf-H2C2_2	119..142	CDD:290200	2/22 (9%)
		C2H2 Zn finger	135..155	CDD:275368	0/19 (0%)
		zf-H2C2_2	147..170	CDD:290200	4/22 (18%)
		C2H2 Zn finger	163..183	CDD:275368	6/19 (32%)
		zf-H2C2_2	175..200	CDD:290200	9/24 (38%)
		C2H2 Zn finger	191..211	CDD:275368	9/19 (47%)
		C2H2 Zn finger	219..239	CDD:275368	6/19 (32%)
		zf-H2C2_2	231..254	CDD:290200	7/23 (30%)
		C2H2 Zn finger	247..267	CDD:275368	7/19 (37%)
		zf-H2C2_2	263..284	CDD:290200	8/21 (38%)
		C2H2 Zn finger	275..295	CDD:275368	8/19 (42%)
		C2H2 Zn finger	331..351	CDD:275368	7/19 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000