Protein Alignment Sry-beta and ZNF30

DIOPT Version :9

• Sequence 1: NP_001303451.1
• Gene: Sry-beta / 43570
• FlyBaseID: FBgn0003511
• Length: 356
• Species: Drosophila melanogaster
• Sequence 2: NP_001092907.1
• Gene: ZNF30 / 90075
• HGNCID: 13090
• Length: 624
• Species: Homo sapiens
• Alignment Length: 277
• Identity: 75/277 - (27%)
• Similarity: 115/277 - (41%)
• Gaps: 42/277 - (15%)

  Fly    82 QIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALKEPERQPGEEDECEEFMKEEMLDE 146
            |:.|..:||:::    .|.:..        |:|.:.|..:.::|.       ||:|:.|
Human    89 QLEDDTIGCKEM----PTSENC--------PSFALHQKISRQKPR-------ECQEYGK------ 128

  Fly   147 EFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVK 211
                :...||.|...|...:......|..||:.||:...|..|.:....:|..:  ...||....
Human   129 ----TLCQDSKPVQHERIHSSEKPNRCKECGKNFSNGHQLTIHQRLHVGEKPYK--YEKCGKAFI 187

  Fly   212 DDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHL 276
            .......|..:|.|:..|:|:.|.|..|....:..|..:|..||.|:|.:||:.|    |:|..|
Human   188 SGSAFVKHGRIHTGEKPLKCKQCGKTISGSYQLTVHKSIHTGKKPYECGECGKAF----LVYGKL 248

  Fly   277 MRHDAE---ENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQ 338
            .||.:.   |....||.|.:.|.|......|.|.|.:::| |.|.:|.|:|.....|..|:|:|.
Human   249 TRHQSTHTGEKPFGCEECGKAFSTFSYLVQHQRIHTSEKP-YECKECGKAFSTSSPLAKHQRIHT 312

  Fly   339 PVEKPESAEAKEATVTF 355
            . |||  .|.||...:|
Human   313 G-EKP--YECKECGKSF 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	3/19 (16%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	17/51 (33%)
		C2H2 Zn finger	288..303	CDD:275370	5/14 (36%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	7/19 (37%)
ZNF30	NP_001092907.1	KRAB	14..75	CDD:214630
		KRAB	14..53	CDD:279668
		COG5048	<97..302	CDD:227381	61/240 (25%)
		C2H2 Zn finger	123..143	CDD:275368	7/29 (24%)
		C2H2 Zn finger	151..171	CDD:275368	7/19 (37%)
		C2H2 Zn finger	179..199	CDD:275368	3/19 (16%)
		C2H2 Zn finger	207..227	CDD:275368	5/19 (26%)
		C2H2 Zn finger	235..255	CDD:275368	9/23 (39%)
		COG5048	245..624	CDD:227381	30/86 (35%)
		C2H2 Zn finger	263..283	CDD:275368	7/19 (37%)
		zf-H2C2_2	275..300	CDD:290200	9/25 (36%)
		C2H2 Zn finger	291..311	CDD:275368	7/19 (37%)
		zf-H2C2_2	304..327	CDD:290200	11/26 (42%)
		C2H2 Zn finger	319..339	CDD:275368	3/8 (38%)
		zf-H2C2_2	332..354	CDD:290200
		C2H2 Zn finger	347..367	CDD:275368
		C2H2 Zn finger	375..395	CDD:275368
		C2H2 Zn finger	403..423	CDD:275368
		zf-H2C2_2	415..438	CDD:290200
		C2H2 Zn finger	431..451	CDD:275368
		zf-H2C2_2	444..466	CDD:290200
		C2H2 Zn finger	459..479	CDD:275368
		zf-H2C2_2	471..496	CDD:290200
		C2H2 Zn finger	487..507	CDD:275368
		zf-H2C2_2	499..524	CDD:290200
		C2H2 Zn finger	515..535	CDD:275368
		zf-H2C2_2	527..551	CDD:290200
		C2H2 Zn finger	543..563	CDD:275368
		C2H2 Zn finger	571..591	CDD:275368
		zf-H2C2_2	584..608	CDD:290200
		C2H2 Zn finger	599..619	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	0	0.000