DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sry-beta and ZFP2

DIOPT Version :9

Sequence 1:NP_001303451.1 Gene:Sry-beta / 43570 FlyBaseID:FBgn0003511 Length:356 Species:Drosophila melanogaster
Sequence 2:NP_085116.2 Gene:ZFP2 / 80108 HGNCID:26138 Length:461 Species:Homo sapiens


Alignment Length:352 Identity:97/352 - (27%)
Similarity:138/352 - (39%) Gaps:55/352 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 RPF-CFVCGK----EKSVGVFQLIEGCIVPGTFKPIK--DILKYFEKIIN----QRLELLPNSAA 58
            :|: |.||||    ..|:.|.|.|.    .|. ||.|  :..|.|.:.:|    ||.........
Human   128 KPYKCNVCGKHFIERSSLTVHQRIH----TGE-KPYKCNECGKAFSQSMNLTVHQRTHTGEKPYQ 187

  Fly    59 CRDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQATALK 123
            |::|.:...      :|.|.:|.:        |...|:...|.....:|..|.....:.|.|...
Human   188 CKECGKAFH------KNSSLIQHE--------RIHTGEKPYKCNECGKAFTQSMNLTVHQRTHTG 238

  Fly   124 EPERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIP--CHICGEMFSSQEVL 186
            |   :|.|.:||.:...:.|.....|.|               .|.|.|  |..||:.||....|
Human   239 E---KPYECNECGKAFSQSMHLIVHQRS---------------HTGEKPYECSQCGKAFSKSSTL 285

  Fly   187 ERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHKRNVLRHMEVH 251
            ..|.:..|.:|..:  ||.||........|..|..||.|....||..|.|.||...::.:|..:|
Human   286 TLHQRNHTGEKPYK--CNKCGKSFSQSTYLIEHQRLHSGVKPFECNECGKAFSKNSSLTQHRRIH 348

  Fly   252 WDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLRTHQTDRPRYP 316
            ..:|.|:|..||:.|:....:..|.:.|..|: ...|..|.:.|........|.|.|..::| |.
Human   349 TGEKPYECMVCGKHFTGRSSLTVHQVIHTGEK-PYECNECGKAFSQSAYLIEHQRIHTGEKP-YE 411

  Fly   317 CPDCEKSFVDKYTLKVHKRVHQPVEKP 343
            |..|.|:|:...:|.||:|.|.. |||
Human   412 CDQCGKAFIKNSSLTVHQRTHTG-EKP 437

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sry-betaNP_001303451.1 C2H2 Zn finger 203..223 CDD:275368 6/19 (32%)
C2H2 Zn finger 231..251 CDD:275368 6/19 (32%)
C2H2 Zn finger 259..308 CDD:275368 12/48 (25%)
C2H2 Zn finger 288..303 CDD:275370 3/14 (21%)
zf-C2H2 315..337 CDD:278523 9/21 (43%)
C2H2 Zn finger 317..337 CDD:275368 8/19 (42%)
ZFP2NP_085116.2 COG5048 99..451 CDD:227381 97/352 (28%)
C2H2 Zn finger 104..124 CDD:275368
C2H2 Zn finger 132..152 CDD:275368 8/19 (42%)
C2H2 Zn finger 160..180 CDD:275368 5/19 (26%)
C2H2 Zn finger 188..208 CDD:275368 6/33 (18%)
C2H2 Zn finger 216..236 CDD:275368 3/19 (16%)
C2H2 Zn finger 244..264 CDD:275368 5/34 (15%)
C2H2 Zn finger 272..292 CDD:275368 7/19 (37%)
C2H2 Zn finger 300..320 CDD:275368 6/19 (32%)
C2H2 Zn finger 328..348 CDD:275368 6/19 (32%)
C2H2 Zn finger 356..376 CDD:275368 5/19 (26%)
C2H2 Zn finger 384..404 CDD:275368 5/19 (26%)
C2H2 Zn finger 412..432 CDD:275368 8/19 (42%)
C2H2 Zn finger 440..460 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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