DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Zfp157

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	XP_006504688.1	Gene:	Zfp157 / 72154	MGIID:	1919404	Length:	582	Species:	Mus musculus

Alignment Length:	310	Identity:	84/310 - (27%)
Similarity:	128/310 - (41%)	Gaps:	37/310 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 PNSAACRDCLEYLFNYDRLVRNLSQVQRQIADALLGCRQVEGKAETKQQAAKRARVQVPAFKIVQ 118
            ||.:...:....::....:.||||..:...|:..:   |:|....||....|      |..|:|.
Mouse    97 PNESCLENAESRMWPVGSINRNLSNKEMIEAEMKV---QLELPRGTKPYECK------PCMKMVS 152

  Fly   119 --ATALKE----PERQPGEEDECEE-FMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHIC 176
              :...|:    |..:|.|..||:: |..:..|              :..:...|......|..|
Mouse   153 LPSQCSKQHAYYPSVKPYEWKECQKAFCYKSAL--------------TQHQRARTRLKIYQCTEC 203

  Fly   177 GEMFSSQEVLERHIKADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYCDKKFSHK 241
            .:.|||:..|..|.:..|.:|..  .|..||........|.:|...|.|:...||:.|.|.|.:|
Mouse   204 KKAFSSKSELTVHHRIHTGEKPH--ACEECGKAFYRKSTLTVHQKTHRGEKPYECKECWKAFYYK 266

  Fly   242 RNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKRTYKHHLR 306
            ..:..|..:|..:|.|.|..||:.|.....:..|...| ..|....|:.|.:.|.:|.....|.|
Mouse   267 STLTEHQRIHTGEKPYVCKDCGKAFFYKSNLTRHHRTH-TREKPYECKECRKGFSSKSELTSHHR 330

  Fly   307 THQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEATVTFF 356
            ||..::| |.|.:|.|:|..|.||:||:::|.. |||  .|.||...:|:
Mouse   331 THTGEKP-YQCEECGKAFYCKSTLRVHQKIHSG-EKP--YECKECQKSFY 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	6/19 (32%)
		C2H2 Zn finger	259..308	CDD:275368	13/48 (27%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	10/21 (48%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
Zfp157	XP_006504688.1	KRAB	19..79	CDD:214630
		C2H2 Zn finger	173..192	CDD:275368	4/32 (13%)
		COG5048	196..550	CDD:227381	60/188 (32%)
		C2H2 Zn finger	200..220	CDD:275368	7/19 (37%)
		C2H2 Zn finger	228..248	CDD:275368	5/19 (26%)
		C2H2 Zn finger	256..276	CDD:275368	6/19 (32%)
		C2H2 Zn finger	284..304	CDD:275368	5/19 (26%)
		C2H2 Zn finger	312..332	CDD:275368	6/19 (32%)
		C2H2 Zn finger	340..360	CDD:275368	9/19 (47%)
		C2H2 Zn finger	368..388	CDD:275368	3/9 (33%)
		C2H2 Zn finger	396..416	CDD:275368
		C2H2 Zn finger	424..444	CDD:275368
		C2H2 Zn finger	452..472	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000