DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and Zfp689

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_780372.2	Gene:	Zfp689 / 71131	MGIID:	1918381	Length:	500	Species:	Mus musculus

Alignment Length:	182	Identity:	59/182 - (32%)
Similarity:	85/182 - (46%)	Gaps:	9/182 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly   172 PCHICGEMFSSQEVLERHIKADT--CQKSEQATCNVCGLKVKDDEVLDLHMNLHEGKTELECRYC 234
            ||..||..||...:|..|.:|.:  |    ...|:.||.:....:.|..|..:|.|:....|..|
Mouse   178 PCPDCGRRFSYPSLLVSHRRAHSGEC----PYVCDQCGKRFSQRKNLSQHQVIHTGEKPYHCPDC 238

  Fly   235 DKKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQQFKTKR 299
            .:.|...|::..|...|..:|.:||..||.||:...|:..|...|..|: ...|..|.::|:.:.
Mouse   239 GRCFRRSRSLANHRTTHTGEKPHQCPSCGRRFAYPSLLAIHQRTHTGEK-PYTCLECSRRFRQRT 302

  Fly   300 TYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAEAKEA 351
            ....|.|.|..::| |||||||:.|.....|..|:|||.. |:|.:.|..||
Mouse   303 ALVIHQRIHTGEKP-YPCPDCERRFSSSSRLVSHRRVHSG-ERPYACENCEA 352

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	5/19 (26%)
		C2H2 Zn finger	231..251	CDD:275368	5/19 (26%)
		C2H2 Zn finger	259..308	CDD:275368	14/48 (29%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	11/21 (52%)
		C2H2 Zn finger	317..337	CDD:275368	9/19 (47%)
Zfp689	NP_780372.2	KRAB	29..88	CDD:214630
		KRAB	29..68	CDD:279668
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	105..144
		C2H2 Zn finger	151..171	CDD:275368
		COG5048	171..>466	CDD:227381	59/182 (32%)
		C2H2 Zn finger	179..199	CDD:275368	7/19 (37%)
		C2H2 Zn finger	207..227	CDD:275368	5/19 (26%)
		zf-H2C2_2	219..244	CDD:290200	7/24 (29%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		zf-H2C2_2	247..272	CDD:290200	9/24 (38%)
		C2H2 Zn finger	263..283	CDD:275368	7/19 (37%)
		zf-H2C2_2	276..300	CDD:290200	6/24 (25%)
		C2H2 Zn finger	291..311	CDD:275368	5/19 (26%)
		zf-H2C2_2	303..328	CDD:290200	12/25 (48%)
		C2H2 Zn finger	319..339	CDD:275368	9/19 (47%)
		zf-H2C2_2	332..356	CDD:290200	10/22 (45%)
		C2H2 Zn finger	347..367	CDD:275368	3/6 (50%)
		zf-H2C2_2	360..384	CDD:290200
		C2H2 Zn finger	375..395	CDD:275368
		C2H2 Zn finger	403..423	CDD:275368
		zf-H2C2_2	416..440	CDD:290200
		C2H2 Zn finger	431..451	CDD:275368
		C2H2 Zn finger	459..475	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000