DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sry-beta and znf711

DIOPT Version :9

Sequence 1:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster
Sequence 2:	NP_001352539.1	Gene:	znf711 / 562505	ZFINID:	ZDB-GENE-081107-49	Length:	765	Species:	Danio rerio

Alignment Length:	310	Identity:	73/310 - (23%)
Similarity:	121/310 - (39%)	Gaps:	65/310 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 NLSQVQRQI-ADALLGCRQVEGKAETKQQAAKRARVQVPAF------------------------ 114
            |.|::..|: .:.::|..:.....|.:.:.:...:..|||.
Zfish   280 NCSEMTDQVYMEVIVGEEEAPAITEAQMEDSPVNKTIVPAAWATAYGSSLESKNGAATPYLQITD 344

  Fly   115 KIVQATALKE--PERQPGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICG 177
            .|..:.|||:  .:|:.||..:|:..|       .|......|..|         .|..||||||
Zfish   345 SISTSRALKQKIKKRRRGETRQCQTGM-------SFSVIIGPDGQP---------LTVYPCHICG 393

  Fly   178 EMFSSQEVLERHIK--ADTCQKSEQATCNVCGLKVKDDEVLDLHMNLHEGK-----------TEL 229
            :.|.|:..|:||:|  .|...| ::..|..|  :...::.:..|.:|...|           ||.
Zfish   394 KKFKSRGFLKRHMKNHPDHMFK-KKYQCTDC--EFTTNKKVSFHNHLESHKLIIKNEKIPEYTEY 455

  Fly   230 ECRYCD-KKFSHKRNVLRHMEVHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALICEVCHQ 293
            ..||.: ...|..:.:||..|    .|.::|..|....:...|:..||:...::..|.:|..|.:
Zfish   456 TRRYHEASPLSSNKLILRDKE----PKLHKCKYCEYETAEQGLLNRHLLAVHSKNFAHVCVECAK 516

  Fly   294 QFKTKRTYKHHLRTHQTDRPRYPCPDCEKSFVDKYTLKVHKRVHQPVEKP 343
            .|:.....|.|:|||..::| :.|..||.|..|:..||.|.:.....:.|
Zfish   517 GFRHPSELKKHMRTHTGEKP-FHCQHCEFSCADQSNLKTHIKSKHGTDLP 565

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	3/19 (16%)
		C2H2 Zn finger	231..251	CDD:275368	6/20 (30%)
		C2H2 Zn finger	259..308	CDD:275368	12/48 (25%)
		C2H2 Zn finger	288..303	CDD:275370	3/14 (21%)
		zf-C2H2	315..337	CDD:278523	8/21 (38%)
		C2H2 Zn finger	317..337	CDD:275368	8/19 (42%)
znf711	NP_001352539.1	Zfx_Zfy_act	64..368	CDD:309717	15/87 (17%)
		COG5048	385..763	CDD:227381	53/189 (28%)
		C2H2 Zn finger	389..409	CDD:275368	11/19 (58%)
		C2H2 Zn finger	482..503	CDD:275368	5/20 (25%)
		C2H2 Zn finger	511..531	CDD:275368	6/19 (32%)
		C2H2 Zn finger	539..560	CDD:275368	8/20 (40%)
		C2H2 Zn finger	568..584	CDD:275368
		C2H2 Zn finger	596..617	CDD:275368
		C2H2 Zn finger	625..645	CDD:275368
		C2H2 Zn finger	682..702	CDD:275368
		C2H2 Zn finger	710..731	CDD:275368
		C2H2 Zn finger	739..759	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100